Low concentrations of Lactobacillus rhamnosus GG ( Yoba®) are safe in male Drosophila melanogaster
Objective: The purpose of the study was to generate information on the safety of probiotics, thus the study objectives were to evaluate the effects of Yoba ® on basic physiochemical properties. The study assessed male w1118 Drosophila melanogaster which were provided food supplemented with Yoba ®...
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BMC Res Notes
2019
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| Online Access: | http://hdl.handle.net/20.500.12493/170 |
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| author | Keneth Iceland, Kasozi Aisha, Bukenya Ejike, Daniel Eze Josephine, Kasolo Dickson Stuart, Tayebwa Fred, Ssempijja Joy, Suubo Andrew, Tamale Isaac, Echoru Ibrahim, Ntulume Sarah, Kemuma Onkoba Lisa Nkatha, Micheni Emmanuel Tiyo, Ayikobua Oscar Hilary, Asiimwe Muhamudu, Kalange |
| author_facet | Keneth Iceland, Kasozi Aisha, Bukenya Ejike, Daniel Eze Josephine, Kasolo Dickson Stuart, Tayebwa Fred, Ssempijja Joy, Suubo Andrew, Tamale Isaac, Echoru Ibrahim, Ntulume Sarah, Kemuma Onkoba Lisa Nkatha, Micheni Emmanuel Tiyo, Ayikobua Oscar Hilary, Asiimwe Muhamudu, Kalange |
| author_sort | Keneth Iceland, Kasozi |
| collection | KAB-DR |
| description | Objective: The purpose of the study was to generate information on the safety of probiotics, thus the study objectives
were to evaluate the effects of Yoba ® on basic physiochemical properties. The study assessed male w1118
Drosophila melanogaster which were provided food supplemented with Yoba ® at 1%, 3%, 6%, and 12% on motor function, total protein, catalase activity, and hydrogen peroxide scavenging activity and lifespan.
Results: Yoba® at high concentration (≥ 6%) increased locomotor activity in Drosophila melanogaster, however, total
protein, catalase, and hydrogen peroxide scavenging activity were significantly higher at 1% Yoba
® compared to 3%, 6%, and 12% Yoba ®. Yoba consumed at 1% was associated with greater physiological benefits in Drosophila melanogaster.
Findings in the study offer a rationale for the consumption of Yoba ® at 1% in humans as is currently being promoted by the Yoba for Life consortium, however, high concentrations of Yoba ® would disrupt physiological function as shown by this study. |
| format | Article |
| id | oai:idr.kab.ac.ug:20.500.12493-170 |
| institution | KAB-DR |
| publishDate | 2019 |
| publisher | BMC Res Notes |
| record_format | dspace |
| spelling | oai:idr.kab.ac.ug:20.500.12493-1702024-01-17T04:44:06Z Low concentrations of Lactobacillus rhamnosus GG ( Yoba®) are safe in male Drosophila melanogaster Keneth Iceland, Kasozi Aisha, Bukenya Ejike, Daniel Eze Josephine, Kasolo Dickson Stuart, Tayebwa Fred, Ssempijja Joy, Suubo Andrew, Tamale Isaac, Echoru Ibrahim, Ntulume Sarah, Kemuma Onkoba Lisa Nkatha, Micheni Emmanuel Tiyo, Ayikobua Oscar Hilary, Asiimwe Muhamudu, Kalange Probiotics, Yoba for life, Nutritional toxicology, Yoghurt, Food supplements, Catalase, Hydrogen peroxide scavenging, Aging Objective: The purpose of the study was to generate information on the safety of probiotics, thus the study objectives were to evaluate the effects of Yoba ® on basic physiochemical properties. The study assessed male w1118 Drosophila melanogaster which were provided food supplemented with Yoba ® at 1%, 3%, 6%, and 12% on motor function, total protein, catalase activity, and hydrogen peroxide scavenging activity and lifespan. Results: Yoba® at high concentration (≥ 6%) increased locomotor activity in Drosophila melanogaster, however, total protein, catalase, and hydrogen peroxide scavenging activity were significantly higher at 1% Yoba ® compared to 3%, 6%, and 12% Yoba ®. Yoba consumed at 1% was associated with greater physiological benefits in Drosophila melanogaster. Findings in the study offer a rationale for the consumption of Yoba ® at 1% in humans as is currently being promoted by the Yoba for Life consortium, however, high concentrations of Yoba ® would disrupt physiological function as shown by this study. Kabale University 2019-06-14T09:37:09Z 2019-06-14T09:37:09Z 2019 Article Kasozi et al http://hdl.handle.net/20.500.12493/170 ;(2019) 12:269 application/pdf BMC Res Notes |
| spellingShingle | Probiotics, Yoba for life, Nutritional toxicology, Yoghurt, Food supplements, Catalase, Hydrogen peroxide scavenging, Aging Keneth Iceland, Kasozi Aisha, Bukenya Ejike, Daniel Eze Josephine, Kasolo Dickson Stuart, Tayebwa Fred, Ssempijja Joy, Suubo Andrew, Tamale Isaac, Echoru Ibrahim, Ntulume Sarah, Kemuma Onkoba Lisa Nkatha, Micheni Emmanuel Tiyo, Ayikobua Oscar Hilary, Asiimwe Muhamudu, Kalange Low concentrations of Lactobacillus rhamnosus GG ( Yoba®) are safe in male Drosophila melanogaster |
| title | Low concentrations of Lactobacillus rhamnosus GG ( Yoba®) are safe in male Drosophila melanogaster |
| title_full | Low concentrations of Lactobacillus rhamnosus GG ( Yoba®) are safe in male Drosophila melanogaster |
| title_fullStr | Low concentrations of Lactobacillus rhamnosus GG ( Yoba®) are safe in male Drosophila melanogaster |
| title_full_unstemmed | Low concentrations of Lactobacillus rhamnosus GG ( Yoba®) are safe in male Drosophila melanogaster |
| title_short | Low concentrations of Lactobacillus rhamnosus GG ( Yoba®) are safe in male Drosophila melanogaster |
| title_sort | low concentrations of lactobacillus rhamnosus gg yoba r are safe in male drosophila melanogaster |
| topic | Probiotics, Yoba for life, Nutritional toxicology, Yoghurt, Food supplements, Catalase, Hydrogen peroxide scavenging, Aging |
| url | http://hdl.handle.net/20.500.12493/170 |
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