Simultaneous non-negative matrix factorization for multiple large scale gene expression datasets in toxicology.

Non-negative matrix factorization is a useful tool for reducing the dimension of large datasets. This work considers simultaneous non-negative matrix factorization of multiple sources of data. In particular, we perform the first study that involves more than two datasets. We discuss the algorithmic...

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Bibliographic Details
Main Authors: Clare M Lee, Manikhandan A V Mudaliar, D R Haggart, C Roland Wolf, Gino Miele, J Keith Vass, Desmond J Higham, Daniel Crowther
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0048238&type=printable
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