Maxillary Swelling as the First Evidence of Multiple Myeloma
Multiple myeloma is a malignant neoplasm of plasma cells characterized by proliferation of a single clone of abnormal immunoglobulin-secreting plasma cells. Since the amount of hemopoietic bone marrow is decreased in the maxilla, oral manifestations of multiple myeloma are less common in the maxilla...
Saved in:
| Main Authors: | , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2015-01-01
|
| Series: | Case Reports in Dentistry |
| Online Access: | http://dx.doi.org/10.1155/2015/439536 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849468153910788096 |
|---|---|
| author | Atsushi Kasamatsu Yasushi Kimura Hideki Tsujimura Harusachi Kanazawa Nao Koide Isao Miyamoto Yosuke Endo-Sakamoto Masashi Shiiba Hideki Tanzawa Katsuhiro Uzawa |
| author_facet | Atsushi Kasamatsu Yasushi Kimura Hideki Tsujimura Harusachi Kanazawa Nao Koide Isao Miyamoto Yosuke Endo-Sakamoto Masashi Shiiba Hideki Tanzawa Katsuhiro Uzawa |
| author_sort | Atsushi Kasamatsu |
| collection | DOAJ |
| description | Multiple myeloma is a malignant neoplasm of plasma cells characterized by proliferation of a single clone of abnormal immunoglobulin-secreting plasma cells. Since the amount of hemopoietic bone marrow is decreased in the maxilla, oral manifestations of multiple myeloma are less common in the maxilla than in the mandible. We report the case of 33-year-old Japanese man who presented with a mass in the right maxillary alveolar region. Computed tomography and magnetic resonance images showed a soft tissue mass in the right maxilla eroding the anterior and lateral walls of the maxillary sinus and extending into the buccal space. The biopsy results, imaging, and laboratory investigations led to the diagnosis of multiple myeloma. This case report suggests that oral surgeons and dentists should properly address oral manifestations as first indications of multiple myeloma. |
| format | Article |
| id | doaj-art-fff91beab29f494eb53ebcae8f6e9edb |
| institution | Kabale University |
| issn | 2090-6447 2090-6455 |
| language | English |
| publishDate | 2015-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Dentistry |
| spelling | doaj-art-fff91beab29f494eb53ebcae8f6e9edb2025-08-20T03:25:56ZengWileyCase Reports in Dentistry2090-64472090-64552015-01-01201510.1155/2015/439536439536Maxillary Swelling as the First Evidence of Multiple MyelomaAtsushi Kasamatsu0Yasushi Kimura1Hideki Tsujimura2Harusachi Kanazawa3Nao Koide4Isao Miyamoto5Yosuke Endo-Sakamoto6Masashi Shiiba7Hideki Tanzawa8Katsuhiro Uzawa9Department of Dentistry and Oral-Maxillofacial Surgery, Chiba University Hospital, 1-8-1 Inohana, Chuo-ku, Chiba 260-8670, JapanDepartment of Oral Science, Graduate School of Medicine, Chiba University, 1-8-1 Inohana, Chuo-ku, Chiba 260-8670, JapanDivision of Clinical Oncology, Chiba Cancer Center, 666-2 Nitona, Chuo-ku, Chiba 260-8717, JapanDivision of Dentistry and Oral and Maxillofacial Surgery, Sammu Medical Center, 167 Naruto, Sammu, Chiba 289-1326, JapanDepartment of Oral Science, Graduate School of Medicine, Chiba University, 1-8-1 Inohana, Chuo-ku, Chiba 260-8670, JapanDepartment of Oral Science, Graduate School of Medicine, Chiba University, 1-8-1 Inohana, Chuo-ku, Chiba 260-8670, JapanDepartment of Dentistry and Oral-Maxillofacial Surgery, Chiba University Hospital, 1-8-1 Inohana, Chuo-ku, Chiba 260-8670, JapanDepartment of Clinical Oncology, Graduate School of Medicine, Chiba University, 1-8-1 Inohana, Chuo-ku, Chiba 260-8670, JapanDepartment of Dentistry and Oral-Maxillofacial Surgery, Chiba University Hospital, 1-8-1 Inohana, Chuo-ku, Chiba 260-8670, JapanDepartment of Dentistry and Oral-Maxillofacial Surgery, Chiba University Hospital, 1-8-1 Inohana, Chuo-ku, Chiba 260-8670, JapanMultiple myeloma is a malignant neoplasm of plasma cells characterized by proliferation of a single clone of abnormal immunoglobulin-secreting plasma cells. Since the amount of hemopoietic bone marrow is decreased in the maxilla, oral manifestations of multiple myeloma are less common in the maxilla than in the mandible. We report the case of 33-year-old Japanese man who presented with a mass in the right maxillary alveolar region. Computed tomography and magnetic resonance images showed a soft tissue mass in the right maxilla eroding the anterior and lateral walls of the maxillary sinus and extending into the buccal space. The biopsy results, imaging, and laboratory investigations led to the diagnosis of multiple myeloma. This case report suggests that oral surgeons and dentists should properly address oral manifestations as first indications of multiple myeloma.http://dx.doi.org/10.1155/2015/439536 |
| spellingShingle | Atsushi Kasamatsu Yasushi Kimura Hideki Tsujimura Harusachi Kanazawa Nao Koide Isao Miyamoto Yosuke Endo-Sakamoto Masashi Shiiba Hideki Tanzawa Katsuhiro Uzawa Maxillary Swelling as the First Evidence of Multiple Myeloma Case Reports in Dentistry |
| title | Maxillary Swelling as the First Evidence of Multiple Myeloma |
| title_full | Maxillary Swelling as the First Evidence of Multiple Myeloma |
| title_fullStr | Maxillary Swelling as the First Evidence of Multiple Myeloma |
| title_full_unstemmed | Maxillary Swelling as the First Evidence of Multiple Myeloma |
| title_short | Maxillary Swelling as the First Evidence of Multiple Myeloma |
| title_sort | maxillary swelling as the first evidence of multiple myeloma |
| url | http://dx.doi.org/10.1155/2015/439536 |
| work_keys_str_mv | AT atsushikasamatsu maxillaryswellingasthefirstevidenceofmultiplemyeloma AT yasushikimura maxillaryswellingasthefirstevidenceofmultiplemyeloma AT hidekitsujimura maxillaryswellingasthefirstevidenceofmultiplemyeloma AT harusachikanazawa maxillaryswellingasthefirstevidenceofmultiplemyeloma AT naokoide maxillaryswellingasthefirstevidenceofmultiplemyeloma AT isaomiyamoto maxillaryswellingasthefirstevidenceofmultiplemyeloma AT yosukeendosakamoto maxillaryswellingasthefirstevidenceofmultiplemyeloma AT masashishiiba maxillaryswellingasthefirstevidenceofmultiplemyeloma AT hidekitanzawa maxillaryswellingasthefirstevidenceofmultiplemyeloma AT katsuhirouzawa maxillaryswellingasthefirstevidenceofmultiplemyeloma |