Rapid and direct discovery of functional tumor specific neoantigens by high resolution mass spectrometry and novel algorithm prediction

Rapid and direct discovery of functional tumor specific neoantigens by high resolution mass spectrometry and novel algorithm prediction

While immune cell therapies have transformed cancer treatment, achieving comparable success in solid tumors remains a significant challenge compared to hematologic malignancies like non-Hodgkin lymphoma (NHL) and multiple myeloma (MM). Over the past four decades, various immunotherapeutic strategies...

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Bibliographic Details
Main Authors: Huajian Tian, Guifei Li, Cookson K.C. Chiu, E. Li, Yuzong Chen, Ting Zhu, Min Hu, Yanjie Wang, Suping Wen, Jiajia Li, Shuangxue Luo, Zhicheng Chen, Huimei Zeng, Nan Zheng, Jinyong Wang, Weijun Shen, Xi Kang
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Cell Insight
Subjects:
Neoantigen
Tumor vaccine
Mass spectrometry
New algorithm
Online Access:http://www.sciencedirect.com/science/article/pii/S2772892725000252
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