Beyond the Masquerade: Primary Follicular Lymphoma Mimicking a Parotid Gland Tumor

Primary follicular lymphoma (PFL) is an uncommon subset of non-Hodgkin lymphoma known for its indolent nature, predominantly afecting lymph nodes. This report presents a rare case of PFL manifesting in the parotid gland, posing challenges in diagnosis and management. A 74-year-old female with pre-au...

Full description

Saved in:
Bibliographic Details
Main Authors: Sana Ahuja, Shaivy Malik, Charanjeet Ahluwalia
Format: Article
Language:English
Published: AVES 2024-04-01
Series:European Journal of Rhinology and Allergy
Online Access:https://www.eurjrhinol.org/en/beyond-the-masquerade-primary-follicular-lymphoma-mimicking-a-parotid-gland-tumor-13188
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1849221167227863040
author Sana Ahuja
Shaivy Malik
Charanjeet Ahluwalia
author_facet Sana Ahuja
Shaivy Malik
Charanjeet Ahluwalia
author_sort Sana Ahuja
collection DOAJ
description Primary follicular lymphoma (PFL) is an uncommon subset of non-Hodgkin lymphoma known for its indolent nature, predominantly afecting lymph nodes. This report presents a rare case of PFL manifesting in the parotid gland, posing challenges in diagnosis and management. A 74-year-old female with pre-auricular swelling underwent diagnostic procedures, including contrast-enhanced computed tomography and fne needle aspiration cytology (FNAC), leading to an initial suspicion of pleomorphic adenoma. Subsequent core needle biopsy confrmed the diagnosis of PFL, highlighting the need for comprehensive diagnostic approaches in unusual presentations. Notably, the patient’s favorable response to chemotherapy aligns with the typical indolent behavior of follicular lymphomas, emphasizing the importance of accurate diagnosis for tailored therapeutic interventions. This case underscores the signifcance of considering lymphoid malignancies in the diferential diagnosis of parotid gland masses and contributes valuable insights into the diagnostic and management complexities of PFL in extranodal sites. Clinicians should remain vigilant to such atypical presentations, recognizing the importance of a multimodal diagnostic approach and personalized treatment strategies.
format Article
id doaj-art-ffec0d05e72a49c9a5b07f617f3313f5
institution Kabale University
issn 2636-8072
language English
publishDate 2024-04-01
publisher AVES
record_format Article
series European Journal of Rhinology and Allergy
spelling doaj-art-ffec0d05e72a49c9a5b07f617f3313f52024-11-19T12:23:48ZengAVESEuropean Journal of Rhinology and Allergy2636-80722024-04-0171384110.5152/ejra.2024.24120Beyond the Masquerade: Primary Follicular Lymphoma Mimicking a Parotid Gland TumorSana Ahuja0Shaivy Malik1Charanjeet Ahluwalia2Department of Pathology, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi, IndiaDepartment of Pathology, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi, IndiaDepartment of Pathology, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi, IndiaPrimary follicular lymphoma (PFL) is an uncommon subset of non-Hodgkin lymphoma known for its indolent nature, predominantly afecting lymph nodes. This report presents a rare case of PFL manifesting in the parotid gland, posing challenges in diagnosis and management. A 74-year-old female with pre-auricular swelling underwent diagnostic procedures, including contrast-enhanced computed tomography and fne needle aspiration cytology (FNAC), leading to an initial suspicion of pleomorphic adenoma. Subsequent core needle biopsy confrmed the diagnosis of PFL, highlighting the need for comprehensive diagnostic approaches in unusual presentations. Notably, the patient’s favorable response to chemotherapy aligns with the typical indolent behavior of follicular lymphomas, emphasizing the importance of accurate diagnosis for tailored therapeutic interventions. This case underscores the signifcance of considering lymphoid malignancies in the diferential diagnosis of parotid gland masses and contributes valuable insights into the diagnostic and management complexities of PFL in extranodal sites. Clinicians should remain vigilant to such atypical presentations, recognizing the importance of a multimodal diagnostic approach and personalized treatment strategies.https://www.eurjrhinol.org/en/beyond-the-masquerade-primary-follicular-lymphoma-mimicking-a-parotid-gland-tumor-13188
spellingShingle Sana Ahuja
Shaivy Malik
Charanjeet Ahluwalia
Beyond the Masquerade: Primary Follicular Lymphoma Mimicking a Parotid Gland Tumor
European Journal of Rhinology and Allergy
title Beyond the Masquerade: Primary Follicular Lymphoma Mimicking a Parotid Gland Tumor
title_full Beyond the Masquerade: Primary Follicular Lymphoma Mimicking a Parotid Gland Tumor
title_fullStr Beyond the Masquerade: Primary Follicular Lymphoma Mimicking a Parotid Gland Tumor
title_full_unstemmed Beyond the Masquerade: Primary Follicular Lymphoma Mimicking a Parotid Gland Tumor
title_short Beyond the Masquerade: Primary Follicular Lymphoma Mimicking a Parotid Gland Tumor
title_sort beyond the masquerade primary follicular lymphoma mimicking a parotid gland tumor
url https://www.eurjrhinol.org/en/beyond-the-masquerade-primary-follicular-lymphoma-mimicking-a-parotid-gland-tumor-13188
work_keys_str_mv AT sanaahuja beyondthemasqueradeprimaryfollicularlymphomamimickingaparotidglandtumor
AT shaivymalik beyondthemasqueradeprimaryfollicularlymphomamimickingaparotidglandtumor
AT charanjeetahluwalia beyondthemasqueradeprimaryfollicularlymphomamimickingaparotidglandtumor