Very-late-onset neuromyelitis optica spectrum disorder: a case report and review
Neuromyelitis optica spectrum disorder (NMOSD) is a rare autoimmune disorder that causes demyelination within the central nervous system, typically manifesting as symptoms of optic neuritis and myelitis. We report the case of a 92-year-old patient with NMOSD who was admitted to our hospital; hers is...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2025-04-01
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| Series: | Frontiers in Neurology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fneur.2025.1559872/full |
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| author | Rui-Ting Liu Yu-Kun Guo Yu-Kun Guo Xia Du Heng Li |
| author_facet | Rui-Ting Liu Yu-Kun Guo Yu-Kun Guo Xia Du Heng Li |
| author_sort | Rui-Ting Liu |
| collection | DOAJ |
| description | Neuromyelitis optica spectrum disorder (NMOSD) is a rare autoimmune disorder that causes demyelination within the central nervous system, typically manifesting as symptoms of optic neuritis and myelitis. We report the case of a 92-year-old patient with NMOSD who was admitted to our hospital; hers is currently the oldest reported case of NMOSD globally. The onset occurred after COVID-19 vaccination, and the patient responded well to treatment with satralizumab. |
| format | Article |
| id | doaj-art-ffd9509a16ef4ceb8ab05caf89b618d1 |
| institution | OA Journals |
| issn | 1664-2295 |
| language | English |
| publishDate | 2025-04-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Neurology |
| spelling | doaj-art-ffd9509a16ef4ceb8ab05caf89b618d12025-08-20T02:16:44ZengFrontiers Media S.A.Frontiers in Neurology1664-22952025-04-011610.3389/fneur.2025.15598721559872Very-late-onset neuromyelitis optica spectrum disorder: a case report and reviewRui-Ting Liu0Yu-Kun Guo1Yu-Kun Guo2Xia Du3Heng Li4Department of Neurology, Central Hospital Affiliated to Shandong First Medical University, Jinan, ChinaDepartment of Neurology, Central Hospital Affiliated to Shandong First Medical University, Jinan, ChinaCheeloo College of Medicine, Shandong University, Jinan, ChinaDepartment of Neurology, Central Hospital Affiliated to Shandong First Medical University, Jinan, ChinaDepartment of Neurology, Central Hospital Affiliated to Shandong First Medical University, Jinan, ChinaNeuromyelitis optica spectrum disorder (NMOSD) is a rare autoimmune disorder that causes demyelination within the central nervous system, typically manifesting as symptoms of optic neuritis and myelitis. We report the case of a 92-year-old patient with NMOSD who was admitted to our hospital; hers is currently the oldest reported case of NMOSD globally. The onset occurred after COVID-19 vaccination, and the patient responded well to treatment with satralizumab.https://www.frontiersin.org/articles/10.3389/fneur.2025.1559872/fullNMOSDvery-late-onsetCOVID-19 vaccineimmunotherapysatralizumab |
| spellingShingle | Rui-Ting Liu Yu-Kun Guo Yu-Kun Guo Xia Du Heng Li Very-late-onset neuromyelitis optica spectrum disorder: a case report and review Frontiers in Neurology NMOSD very-late-onset COVID-19 vaccine immunotherapy satralizumab |
| title | Very-late-onset neuromyelitis optica spectrum disorder: a case report and review |
| title_full | Very-late-onset neuromyelitis optica spectrum disorder: a case report and review |
| title_fullStr | Very-late-onset neuromyelitis optica spectrum disorder: a case report and review |
| title_full_unstemmed | Very-late-onset neuromyelitis optica spectrum disorder: a case report and review |
| title_short | Very-late-onset neuromyelitis optica spectrum disorder: a case report and review |
| title_sort | very late onset neuromyelitis optica spectrum disorder a case report and review |
| topic | NMOSD very-late-onset COVID-19 vaccine immunotherapy satralizumab |
| url | https://www.frontiersin.org/articles/10.3389/fneur.2025.1559872/full |
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