Novel Approaches to Surfactant Administration

Surfactant replacement therapy has been the mainstay of treatment for preterm infants with respiratory distress syndrome for more than twenty years. For the most part, surfactant is administered intratracheally, followed by mechanical ventilation. In recent years, the growing interest in noninvasive...

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Main Authors: Samir Gupta, Steven M. Donn
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:Critical Care Research and Practice
Online Access:http://dx.doi.org/10.1155/2012/278483
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author Samir Gupta
Steven M. Donn
author_facet Samir Gupta
Steven M. Donn
author_sort Samir Gupta
collection DOAJ
description Surfactant replacement therapy has been the mainstay of treatment for preterm infants with respiratory distress syndrome for more than twenty years. For the most part, surfactant is administered intratracheally, followed by mechanical ventilation. In recent years, the growing interest in noninvasive ventilation has led to novel approaches of administration. This paper will review these techniques and the associated clinical evidence.
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series Critical Care Research and Practice
spelling doaj-art-ffd5b58898c54f1e92984a783daf9f9c2025-02-03T05:47:14ZengWileyCritical Care Research and Practice2090-13052090-13132012-01-01201210.1155/2012/278483278483Novel Approaches to Surfactant AdministrationSamir Gupta0Steven M. Donn1University Hospital of North Tees and Durham University, Hardwick Road, Stockton-on-Tees, Cleveland, OH TS19 8PE, UKDivision of Neonatal-Perinatal Medicine, C. S. Mott Children’s Hospital, University of Michigan Health System, Ann Arbor, MI 48109-4254, USASurfactant replacement therapy has been the mainstay of treatment for preterm infants with respiratory distress syndrome for more than twenty years. For the most part, surfactant is administered intratracheally, followed by mechanical ventilation. In recent years, the growing interest in noninvasive ventilation has led to novel approaches of administration. This paper will review these techniques and the associated clinical evidence.http://dx.doi.org/10.1155/2012/278483
spellingShingle Samir Gupta
Steven M. Donn
Novel Approaches to Surfactant Administration
Critical Care Research and Practice
title Novel Approaches to Surfactant Administration
title_full Novel Approaches to Surfactant Administration
title_fullStr Novel Approaches to Surfactant Administration
title_full_unstemmed Novel Approaches to Surfactant Administration
title_short Novel Approaches to Surfactant Administration
title_sort novel approaches to surfactant administration
url http://dx.doi.org/10.1155/2012/278483
work_keys_str_mv AT samirgupta novelapproachestosurfactantadministration
AT stevenmdonn novelapproachestosurfactantadministration