Role of 5-aminosalicylic acid in ulcerative colitis management in 8 Asian territories: a physician survey
Clinical guidelines typically endorse conventional therapies such as 5-aminosalicylic acid (5-ASA) as the mainstay of ulcerative colitis management. However, the degree of adoption and application of guideline recommendations by physicians within Asia remains unclear. This study aims to understand t...
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| Format: | Article |
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Korean Association for the Study of Intestinal Diseases
2025-04-01
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| Series: | Intestinal Research |
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| Online Access: | http://irjournal.org/upload/pdf/ir-2024-00085.pdf |
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| author | Julajak Limsrivilai Allen Yu-hung Lai Silvia T. H. Li Murdani Abdullah Raja Affendi Raja Ali Satimai Aniwan Hoang Huu Bui Jen-Wei Chou Ida Normiha Hilmi Wee Chian Lim Jose Sollano Michelle Mui Hian Teo Shu-Chen Wei Wai Keung Leung |
| author_facet | Julajak Limsrivilai Allen Yu-hung Lai Silvia T. H. Li Murdani Abdullah Raja Affendi Raja Ali Satimai Aniwan Hoang Huu Bui Jen-Wei Chou Ida Normiha Hilmi Wee Chian Lim Jose Sollano Michelle Mui Hian Teo Shu-Chen Wei Wai Keung Leung |
| author_sort | Julajak Limsrivilai |
| collection | DOAJ |
| description | Clinical guidelines typically endorse conventional therapies such as 5-aminosalicylic acid (5-ASA) as the mainstay of ulcerative colitis management. However, the degree of adoption and application of guideline recommendations by physicians within Asia remains unclear. This study aims to understand the prescribing patterns of 5-ASA and implementation of current guideline recommendations across Asian clinical practice. A physician survey was conducted among inflammatory bowel disease specialists in 8 Asian territories to understand practices and preferences in ulcerative colitis management, focusing on the use of 5-ASA and concordance with guideline recommendations. Survey findings were validated by country experts in diverse healthcare settings. Subgroup analyses stratified data by income levels and treatment reimbursement status. Ninety-eight valid responses were received from inflammatory bowel disease specialists or gastroenterologists among 8 economic entities. Significant differences were found in clinical practices and treatment preferences for ulcerative colitis management among different income-level and government-subsidy groups. Survey results are summarized in 8 findings that illustrate trends in 5-ASA use and guideline implementation across Asian territories. This study emphasizes socioeconomic factors that impact the adoption of guideline recommendations in real-world practice. Our findings indicate an eclectic approach to guideline implementation across Asia, based on resource availability and feasibility of treatment goals. |
| format | Article |
| id | doaj-art-ffd356d86baf4d6aaa6c4b232b14fba7 |
| institution | OA Journals |
| issn | 1598-9100 2288-1956 |
| language | English |
| publishDate | 2025-04-01 |
| publisher | Korean Association for the Study of Intestinal Diseases |
| record_format | Article |
| series | Intestinal Research |
| spelling | doaj-art-ffd356d86baf4d6aaa6c4b232b14fba72025-08-20T01:52:15ZengKorean Association for the Study of Intestinal DiseasesIntestinal Research1598-91002288-19562025-04-0123211712810.5217/ir.2024.000851096Role of 5-aminosalicylic acid in ulcerative colitis management in 8 Asian territories: a physician surveyJulajak Limsrivilai0Allen Yu-hung Lai1Silvia T. H. Li2Murdani Abdullah3Raja Affendi Raja Ali4Satimai Aniwan5Hoang Huu Bui6Jen-Wei Chou7Ida Normiha Hilmi8Wee Chian Lim9Jose Sollano10Michelle Mui Hian Teo11Shu-Chen Wei12Wai Keung Leung13 Division of Gastroenterology, Siriraj Hospital, Mahidol University, Bangkok, Thailand Global Health Program, College of Public Health, National Taiwan University, Taipei, Taiwan Centre for Safe Medication Practice and Research, Department of Pharmacology and Pharmacy, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China Division of Gastroenterology, Pancreatobiliary, and Digestive Endoscopy, Department of Internal Medicine, Human Cancer Research Center - Indonesian Medical Education and Research Institute, Faculty of Medicine/Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia School of Medical and Life Sciences, Sunway University, Kuala Lumpur, Malaysia Department of Medicine, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand Department of Gastroenterology, University Medical Center, Ho Chi Minh City, Vietnam Center for Digestive Medicine, Department of Internal Medicine, China Medical University Hospital, Taichung, Taiwan Division of Gastroenterology and Hepatology, Department of Medicine, University Malaya, Kuala Lumpur, Malaysia Department of Gastroenterology and Hepatology, Tan Tock Seng Hospital, Singapore Faculty of Medicine and Surgery, University of Santo Tomas, Manila, Philippines Ferring Pharmaceuticals Ltd., Singapore Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan Department of Medicine, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, ChinaClinical guidelines typically endorse conventional therapies such as 5-aminosalicylic acid (5-ASA) as the mainstay of ulcerative colitis management. However, the degree of adoption and application of guideline recommendations by physicians within Asia remains unclear. This study aims to understand the prescribing patterns of 5-ASA and implementation of current guideline recommendations across Asian clinical practice. A physician survey was conducted among inflammatory bowel disease specialists in 8 Asian territories to understand practices and preferences in ulcerative colitis management, focusing on the use of 5-ASA and concordance with guideline recommendations. Survey findings were validated by country experts in diverse healthcare settings. Subgroup analyses stratified data by income levels and treatment reimbursement status. Ninety-eight valid responses were received from inflammatory bowel disease specialists or gastroenterologists among 8 economic entities. Significant differences were found in clinical practices and treatment preferences for ulcerative colitis management among different income-level and government-subsidy groups. Survey results are summarized in 8 findings that illustrate trends in 5-ASA use and guideline implementation across Asian territories. This study emphasizes socioeconomic factors that impact the adoption of guideline recommendations in real-world practice. Our findings indicate an eclectic approach to guideline implementation across Asia, based on resource availability and feasibility of treatment goals.http://irjournal.org/upload/pdf/ir-2024-00085.pdfulcerative colitisguidelines5-aminosalicylatesmesalamineinflammatory bowel diseases |
| spellingShingle | Julajak Limsrivilai Allen Yu-hung Lai Silvia T. H. Li Murdani Abdullah Raja Affendi Raja Ali Satimai Aniwan Hoang Huu Bui Jen-Wei Chou Ida Normiha Hilmi Wee Chian Lim Jose Sollano Michelle Mui Hian Teo Shu-Chen Wei Wai Keung Leung Role of 5-aminosalicylic acid in ulcerative colitis management in 8 Asian territories: a physician survey Intestinal Research ulcerative colitis guidelines 5-aminosalicylates mesalamine inflammatory bowel diseases |
| title | Role of 5-aminosalicylic acid in ulcerative colitis management in 8 Asian territories: a physician survey |
| title_full | Role of 5-aminosalicylic acid in ulcerative colitis management in 8 Asian territories: a physician survey |
| title_fullStr | Role of 5-aminosalicylic acid in ulcerative colitis management in 8 Asian territories: a physician survey |
| title_full_unstemmed | Role of 5-aminosalicylic acid in ulcerative colitis management in 8 Asian territories: a physician survey |
| title_short | Role of 5-aminosalicylic acid in ulcerative colitis management in 8 Asian territories: a physician survey |
| title_sort | role of 5 aminosalicylic acid in ulcerative colitis management in 8 asian territories a physician survey |
| topic | ulcerative colitis guidelines 5-aminosalicylates mesalamine inflammatory bowel diseases |
| url | http://irjournal.org/upload/pdf/ir-2024-00085.pdf |
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