Insulin Autoimmune Syndrome: A Chinese Expert Consensus Statement

ABSTRACT Insulin autoimmune syndrome (IAS) is a rare autoimmune disorder characterized by spontaneous hypoglycemia. The incidence of IAS is higher in East Asian populations compared to other populations. Delayed diagnosis and treatment can lead to recurrent hypoglycemia, significant glucose fluctuat...

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Main Authors: Huabing Zhang, Ming Xia Yuan, Qi Pan
Format: Article
Language:English
Published: Wiley 2025-02-01
Series:Aging Medicine
Subjects:
Online Access:https://doi.org/10.1002/agm2.70007
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author Huabing Zhang
Ming Xia Yuan
Qi Pan
author_facet Huabing Zhang
Ming Xia Yuan
Qi Pan
author_sort Huabing Zhang
collection DOAJ
description ABSTRACT Insulin autoimmune syndrome (IAS) is a rare autoimmune disorder characterized by spontaneous hypoglycemia. The incidence of IAS is higher in East Asian populations compared to other populations. Delayed diagnosis and treatment can lead to recurrent hypoglycemia, significant glucose fluctuations, and adverse clinical outcomes, including life‐threatening situations. Currently, no standardized guidelines exist for the diagnosis and treatment of IAS. This consensus aims to provide a systematic summary of the epidemiology, triggers, pathogenesis, clinical manifestations, diagnosis, differential diagnosis, treatment, and prognosis of IAS, with the objective of standardizing its clinical management.
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spelling doaj-art-ffccc8eeba5e4eb1a3b495bee12ab4d22025-08-20T02:55:06ZengWileyAging Medicine2475-03602025-02-0181n/an/a10.1002/agm2.70007Insulin Autoimmune Syndrome: A Chinese Expert Consensus StatementHuabing Zhang0Ming Xia Yuan1Qi Pan2Department of Endocrinology, Peking Union Medical College Hospital Chinese Academy of Medical Sciences Beijing ChinaDepartment of Endocrinology, Beijing Friendship Hospital Capital Medical University Beijing ChinaDepartment of Endocrinology, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine Chinese Academy of Medical Sciences Beijing ChinaABSTRACT Insulin autoimmune syndrome (IAS) is a rare autoimmune disorder characterized by spontaneous hypoglycemia. The incidence of IAS is higher in East Asian populations compared to other populations. Delayed diagnosis and treatment can lead to recurrent hypoglycemia, significant glucose fluctuations, and adverse clinical outcomes, including life‐threatening situations. Currently, no standardized guidelines exist for the diagnosis and treatment of IAS. This consensus aims to provide a systematic summary of the epidemiology, triggers, pathogenesis, clinical manifestations, diagnosis, differential diagnosis, treatment, and prognosis of IAS, with the objective of standardizing its clinical management.https://doi.org/10.1002/agm2.70007chinese expert consensushypoglycemiainsulin autoimmune syndrome
spellingShingle Huabing Zhang
Ming Xia Yuan
Qi Pan
Insulin Autoimmune Syndrome: A Chinese Expert Consensus Statement
Aging Medicine
chinese expert consensus
hypoglycemia
insulin autoimmune syndrome
title Insulin Autoimmune Syndrome: A Chinese Expert Consensus Statement
title_full Insulin Autoimmune Syndrome: A Chinese Expert Consensus Statement
title_fullStr Insulin Autoimmune Syndrome: A Chinese Expert Consensus Statement
title_full_unstemmed Insulin Autoimmune Syndrome: A Chinese Expert Consensus Statement
title_short Insulin Autoimmune Syndrome: A Chinese Expert Consensus Statement
title_sort insulin autoimmune syndrome a chinese expert consensus statement
topic chinese expert consensus
hypoglycemia
insulin autoimmune syndrome
url https://doi.org/10.1002/agm2.70007
work_keys_str_mv AT huabingzhang insulinautoimmunesyndromeachineseexpertconsensusstatement
AT mingxiayuan insulinautoimmunesyndromeachineseexpertconsensusstatement
AT qipan insulinautoimmunesyndromeachineseexpertconsensusstatement