How Colposcopy Misses Invasive Cervical Cancer: A Case Report from the IMPROVE-COLPO Study
Colposcopy with biopsy is pivotal to cervical cancer prevention programs as it is called to identify the precancerous lesions on patients that screen positive. We present a cervical cancer case from IMPROVE-COLPO, a postmarketing, multicenter, two-arm observational study on US community colposcopy t...
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| Format: | Article |
| Language: | English |
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Wiley
2016-01-01
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| Series: | Case Reports in Obstetrics and Gynecology |
| Online Access: | http://dx.doi.org/10.1155/2016/5857370 |
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| author | Jeff Livingston Emmanouil Papagiannakis |
| author_facet | Jeff Livingston Emmanouil Papagiannakis |
| author_sort | Jeff Livingston |
| collection | DOAJ |
| description | Colposcopy with biopsy is pivotal to cervical cancer prevention programs as it is called to identify the precancerous lesions on patients that screen positive. We present a cervical cancer case from IMPROVE-COLPO, a postmarketing, multicenter, two-arm observational study on US community colposcopy that collects outcomes with the adjunctive Dynamic Spectral Imaging (DSI) in its prospective arm. A 45-year-old woman was seen for suffering of heavy periods. She had cytology of Atypical Squamous Cells of Undetermined Significance (ASC-US) and was Human Papillomavirus (HPV) positive. Her colposcopy did not recognize the underlying condition and opted for no biopsy. The DSI assessment led to a biopsy of a lesion challenging traditional colposcopic templates: small, away from the cervical os, with slow acetowhitening development. Pathology review revealed the presence of invasive squamous carcinoma. In the era of sensitive screening, it is concerning that invasive cancers can challenge colposcopy and that the way to improve colposcopy is to collect multiple biopsies from each patient. The case presented indicates that the adjunctive objective assessment by DSI increases reassurance that observations outside of traditional standard visual templates are not underestimated or ignored. |
| format | Article |
| id | doaj-art-ffcbabccebee40f8a7651dd65d2f40eb |
| institution | Kabale University |
| issn | 2090-6684 2090-6692 |
| language | English |
| publishDate | 2016-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Obstetrics and Gynecology |
| spelling | doaj-art-ffcbabccebee40f8a7651dd65d2f40eb2025-08-20T03:25:54ZengWileyCase Reports in Obstetrics and Gynecology2090-66842090-66922016-01-01201610.1155/2016/58573705857370How Colposcopy Misses Invasive Cervical Cancer: A Case Report from the IMPROVE-COLPO StudyJeff Livingston0Emmanouil Papagiannakis1MacArthur OB/GYN, Irving, TX, USADySIS Medical Inc, Tampa, FL, USAColposcopy with biopsy is pivotal to cervical cancer prevention programs as it is called to identify the precancerous lesions on patients that screen positive. We present a cervical cancer case from IMPROVE-COLPO, a postmarketing, multicenter, two-arm observational study on US community colposcopy that collects outcomes with the adjunctive Dynamic Spectral Imaging (DSI) in its prospective arm. A 45-year-old woman was seen for suffering of heavy periods. She had cytology of Atypical Squamous Cells of Undetermined Significance (ASC-US) and was Human Papillomavirus (HPV) positive. Her colposcopy did not recognize the underlying condition and opted for no biopsy. The DSI assessment led to a biopsy of a lesion challenging traditional colposcopic templates: small, away from the cervical os, with slow acetowhitening development. Pathology review revealed the presence of invasive squamous carcinoma. In the era of sensitive screening, it is concerning that invasive cancers can challenge colposcopy and that the way to improve colposcopy is to collect multiple biopsies from each patient. The case presented indicates that the adjunctive objective assessment by DSI increases reassurance that observations outside of traditional standard visual templates are not underestimated or ignored.http://dx.doi.org/10.1155/2016/5857370 |
| spellingShingle | Jeff Livingston Emmanouil Papagiannakis How Colposcopy Misses Invasive Cervical Cancer: A Case Report from the IMPROVE-COLPO Study Case Reports in Obstetrics and Gynecology |
| title | How Colposcopy Misses Invasive Cervical Cancer: A Case Report from the IMPROVE-COLPO Study |
| title_full | How Colposcopy Misses Invasive Cervical Cancer: A Case Report from the IMPROVE-COLPO Study |
| title_fullStr | How Colposcopy Misses Invasive Cervical Cancer: A Case Report from the IMPROVE-COLPO Study |
| title_full_unstemmed | How Colposcopy Misses Invasive Cervical Cancer: A Case Report from the IMPROVE-COLPO Study |
| title_short | How Colposcopy Misses Invasive Cervical Cancer: A Case Report from the IMPROVE-COLPO Study |
| title_sort | how colposcopy misses invasive cervical cancer a case report from the improve colpo study |
| url | http://dx.doi.org/10.1155/2016/5857370 |
| work_keys_str_mv | AT jefflivingston howcolposcopymissesinvasivecervicalcanceracasereportfromtheimprovecolpostudy AT emmanouilpapagiannakis howcolposcopymissesinvasivecervicalcanceracasereportfromtheimprovecolpostudy |