EXAMINATION OF PERIPHERAL LYMPH NODES USING SHEAR WAVE ELASTOGRAPHY IN PATIENTS WITH HEAD AND NECK CANCER

Between December and September 2018 123 patients with head and neck tumors underwent ultrasound examination. The median age of the patients was 57 years (range 19–76 years). Metastatic lymph nodes were suspected in all patients. A fine needle aspiration biopsy was performed prior to treatment. Aplio...

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Main Authors: D. A. Lezhnev, A. Yu. Vasilyev, E. A. Egorova, M. V. Smyslenova, V. P. Truten, V. V. Petrovskaya, A. I. Gromov, O. V. Kostash, Yu. V. Kabin, V. V. Kapustin
Format: Article
Language:Russian
Published: Russian Academy of Sciences, Tomsk National Research Medical Center 2019-06-01
Series:Сибирский онкологический журнал
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Online Access:https://www.siboncoj.ru/jour/article/view/1090
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author D. A. Lezhnev
A. Yu. Vasilyev
E. A. Egorova
M. V. Smyslenova
V. P. Truten
V. V. Petrovskaya
A. I. Gromov
O. V. Kostash
Yu. V. Kabin
V. V. Kapustin
author_facet D. A. Lezhnev
A. Yu. Vasilyev
E. A. Egorova
M. V. Smyslenova
V. P. Truten
V. V. Petrovskaya
A. I. Gromov
O. V. Kostash
Yu. V. Kabin
V. V. Kapustin
author_sort D. A. Lezhnev
collection DOAJ
description Between December and September 2018 123 patients with head and neck tumors underwent ultrasound examination. The median age of the patients was 57 years (range 19–76 years). Metastatic lymph nodes were suspected in all patients. A fine needle aspiration biopsy was performed prior to treatment. Aplio 500 (Тoshiba, Japan) ultrasound device was used. According to findings of cytological examination, all patients were divided into 2 groups. Group I consisted of 58 patients with cytologically confirmed metastatic lymph nodes. Group II comprised 65 patients with lymphoid reticular hyperplasia. The values of Young’s modulus for metastatic lymph nodes were: median – 134.2 kPa, 2.5–97.5 percentiles – 7.3–181.7 kPa. The corresponding values for hyperplastic lymph nodes were: 20.1 kPa, 6.9–138.3 kPa. Thus, significant differences in the values of Young’s modulus between metastatic and hyperplastic lymph nodes were detected in patients with head and neck cancer (p<0.001). The best diagnostic values for detecting metastatic lymph nodes in patients with head and neck cancer were achieved with a threshold value of the Young’s modulus of 33.2 kPa (sensitivity – 89.7 %, specificity – 84.6 %), AU C – 0.899. The values of the Young’s modulus in the metastatic lymph nodes did not depend on the primary tumor and on the localization of the lymph nodes studied (submandibular, paratracheal, cervical, supraclavicular groups).
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publisher Russian Academy of Sciences, Tomsk National Research Medical Center
record_format Article
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spelling doaj-art-ffc4f5a156f7491ea6bb6ebf25db450c2025-08-20T02:59:08ZrusRussian Academy of Sciences, Tomsk National Research Medical CenterСибирский онкологический журнал1814-48612312-31682019-06-0118351310.21294/1814-4861-2019-18-3-5-13636EXAMINATION OF PERIPHERAL LYMPH NODES USING SHEAR WAVE ELASTOGRAPHY IN PATIENTS WITH HEAD AND NECK CANCERD. A. Lezhnev0A. Yu. Vasilyev1E. A. Egorova2M. V. Smyslenova3V. P. Truten4V. V. Petrovskaya5A. I. Gromov6O. V. Kostash7Yu. V. Kabin8V. V. Kapustin9Moscow State University of Medicine and Dentistry named after EvdokimovMoscow State University of Medicine and Dentistry named after EvdokimovMoscow State University of Medicine and Dentistry named after EvdokimovMoscow State University of Medicine and Dentistry named after EvdokimovMoscow State University of Medicine and Dentistry named after EvdokimovMoscow State University of Medicine and Dentistry named after EvdokimovMoscow State University of Medicine and Dentistry named after EvdokimovMoscow Municipal Cancer Hospital №62Moscow Municipal Cancer Hospital №62Moscow Municipal Cancer Hospital №62Between December and September 2018 123 patients with head and neck tumors underwent ultrasound examination. The median age of the patients was 57 years (range 19–76 years). Metastatic lymph nodes were suspected in all patients. A fine needle aspiration biopsy was performed prior to treatment. Aplio 500 (Тoshiba, Japan) ultrasound device was used. According to findings of cytological examination, all patients were divided into 2 groups. Group I consisted of 58 patients with cytologically confirmed metastatic lymph nodes. Group II comprised 65 patients with lymphoid reticular hyperplasia. The values of Young’s modulus for metastatic lymph nodes were: median – 134.2 kPa, 2.5–97.5 percentiles – 7.3–181.7 kPa. The corresponding values for hyperplastic lymph nodes were: 20.1 kPa, 6.9–138.3 kPa. Thus, significant differences in the values of Young’s modulus between metastatic and hyperplastic lymph nodes were detected in patients with head and neck cancer (p<0.001). The best diagnostic values for detecting metastatic lymph nodes in patients with head and neck cancer were achieved with a threshold value of the Young’s modulus of 33.2 kPa (sensitivity – 89.7 %, specificity – 84.6 %), AU C – 0.899. The values of the Young’s modulus in the metastatic lymph nodes did not depend on the primary tumor and on the localization of the lymph nodes studied (submandibular, paratracheal, cervical, supraclavicular groups).https://www.siboncoj.ru/jour/article/view/1090ultrasound elastographyshare wave elastographylymph nodesyoung’s modulus. share wave velocitymetastases
spellingShingle D. A. Lezhnev
A. Yu. Vasilyev
E. A. Egorova
M. V. Smyslenova
V. P. Truten
V. V. Petrovskaya
A. I. Gromov
O. V. Kostash
Yu. V. Kabin
V. V. Kapustin
EXAMINATION OF PERIPHERAL LYMPH NODES USING SHEAR WAVE ELASTOGRAPHY IN PATIENTS WITH HEAD AND NECK CANCER
Сибирский онкологический журнал
ultrasound elastography
share wave elastography
lymph nodes
young’s modulus. share wave velocity
metastases
title EXAMINATION OF PERIPHERAL LYMPH NODES USING SHEAR WAVE ELASTOGRAPHY IN PATIENTS WITH HEAD AND NECK CANCER
title_full EXAMINATION OF PERIPHERAL LYMPH NODES USING SHEAR WAVE ELASTOGRAPHY IN PATIENTS WITH HEAD AND NECK CANCER
title_fullStr EXAMINATION OF PERIPHERAL LYMPH NODES USING SHEAR WAVE ELASTOGRAPHY IN PATIENTS WITH HEAD AND NECK CANCER
title_full_unstemmed EXAMINATION OF PERIPHERAL LYMPH NODES USING SHEAR WAVE ELASTOGRAPHY IN PATIENTS WITH HEAD AND NECK CANCER
title_short EXAMINATION OF PERIPHERAL LYMPH NODES USING SHEAR WAVE ELASTOGRAPHY IN PATIENTS WITH HEAD AND NECK CANCER
title_sort examination of peripheral lymph nodes using shear wave elastography in patients with head and neck cancer
topic ultrasound elastography
share wave elastography
lymph nodes
young’s modulus. share wave velocity
metastases
url https://www.siboncoj.ru/jour/article/view/1090
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