The Effect of Dietary Protein Intake on the Risk of Gestational Diabetes

Background. The results of epidemiological studies on the association between dietary protein intake and gestational diabetes mellitus (GDM) are controversial. Thus, this systematic review and meta-analysis of cohort studies were established to attain comprehensive findings regarding the association...

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Main Authors: Lingling Chen, Shuli Du, Honghua Song, Jing Chen, Cuiting Lv, Chunhui Li
Format: Article
Language:English
Published: Wiley 2022-01-01
Series:Journal of Food Quality
Online Access:http://dx.doi.org/10.1155/2022/8368113
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author Lingling Chen
Shuli Du
Honghua Song
Jing Chen
Cuiting Lv
Chunhui Li
author_facet Lingling Chen
Shuli Du
Honghua Song
Jing Chen
Cuiting Lv
Chunhui Li
author_sort Lingling Chen
collection DOAJ
description Background. The results of epidemiological studies on the association between dietary protein intake and gestational diabetes mellitus (GDM) are controversial. Thus, this systematic review and meta-analysis of cohort studies were established to attain comprehensive findings regarding the association between dietary protein and the risk of GDM. Methods. Bibliographic databases including PubMed, Scopus, Web of Science, and Google Scholar were searched to discover papers related to dietary protein and the risk of GDM. The summary relative risks with 95% confidence intervals (CIs) were estimated through a random effect model for the analysis of the highest versus the lowest categories of dietary proteins. Results. A significantly increased risk of GDM among women who consumed the highest amount of animal protein was observed (summarized risk estimate: 1.52; 95% CI: 1.07, 2.17; I2 = 50.8%). No significant associations were identified regarding vegetable protein (summarized risk estimate:0.99, 95% CI: 0.80 to 1.23, I2 = 63.8%) and total protein (summarized risk estimate: 1.12; 95% CI: 0.88, 1.41; I2 = 35.4%). Conclusion. This review revealed that total protein intake had no relationship with the risk of GDM, while animal protein increases this risk. Further larger prospective cohort studies are required to confirm our results.
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spelling doaj-art-ffbb5d8963634c51a7be97f28be716e92025-08-20T02:22:50ZengWileyJournal of Food Quality1745-45572022-01-01202210.1155/2022/8368113The Effect of Dietary Protein Intake on the Risk of Gestational DiabetesLingling Chen0Shuli Du1Honghua Song2Jing Chen3Cuiting Lv4Chunhui Li5Department of ObstetricsDepartment of ObstetricsDepartment of ObstetricsDepartment of ObstetricsDepartment of Reproductive MedicineNeurosurgeryBackground. The results of epidemiological studies on the association between dietary protein intake and gestational diabetes mellitus (GDM) are controversial. Thus, this systematic review and meta-analysis of cohort studies were established to attain comprehensive findings regarding the association between dietary protein and the risk of GDM. Methods. Bibliographic databases including PubMed, Scopus, Web of Science, and Google Scholar were searched to discover papers related to dietary protein and the risk of GDM. The summary relative risks with 95% confidence intervals (CIs) were estimated through a random effect model for the analysis of the highest versus the lowest categories of dietary proteins. Results. A significantly increased risk of GDM among women who consumed the highest amount of animal protein was observed (summarized risk estimate: 1.52; 95% CI: 1.07, 2.17; I2 = 50.8%). No significant associations were identified regarding vegetable protein (summarized risk estimate:0.99, 95% CI: 0.80 to 1.23, I2 = 63.8%) and total protein (summarized risk estimate: 1.12; 95% CI: 0.88, 1.41; I2 = 35.4%). Conclusion. This review revealed that total protein intake had no relationship with the risk of GDM, while animal protein increases this risk. Further larger prospective cohort studies are required to confirm our results.http://dx.doi.org/10.1155/2022/8368113
spellingShingle Lingling Chen
Shuli Du
Honghua Song
Jing Chen
Cuiting Lv
Chunhui Li
The Effect of Dietary Protein Intake on the Risk of Gestational Diabetes
Journal of Food Quality
title The Effect of Dietary Protein Intake on the Risk of Gestational Diabetes
title_full The Effect of Dietary Protein Intake on the Risk of Gestational Diabetes
title_fullStr The Effect of Dietary Protein Intake on the Risk of Gestational Diabetes
title_full_unstemmed The Effect of Dietary Protein Intake on the Risk of Gestational Diabetes
title_short The Effect of Dietary Protein Intake on the Risk of Gestational Diabetes
title_sort effect of dietary protein intake on the risk of gestational diabetes
url http://dx.doi.org/10.1155/2022/8368113
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