Differential transport pathways of saturated and unsaturated fatty acid esters in male mouse hepatocytes

Abstract Saturated fatty acid (SFA) and unsaturated fatty acid (UFA) have distinct impacts on health. Whether SFA and UFA are differentially transported in liver remains elusive. Here, we find the secretion of UFA but not SFA esters is retarded in a male mouse hepatic endoplasmic reticulum (ER) stre...

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Bibliographic Details
Main Authors: Fengwu Chen, Aizhen Yang, Yue Lu, Yuxin Zhang, Jingyu Zhang, Jianan Bu, Runlin Guo, Yue Han, Depei Wu, Yi Wu
Format: Article
Language:English
Published: Nature Portfolio 2025-02-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-56620-4
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