Data‐driven discovery of associations between prescribed drugs and dementia risk: A systematic review

Data‐driven discovery of associations between prescribed drugs and dementia risk: A systematic review

Abstract Recent clinical trials on slowing dementia progression have led to renewed focus on finding safer, more effective treatments. One approach to identify plausible candidates is to assess whether existing medications for other conditions may affect dementia risk. We conducted a systematic revi...

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Main Authors: Benjamin R. Underwood, Ilianna Lourida, Jessica Gong, Stefano Tamburin, Eugene Yee Hing Tang, Emad Sidhom, Xin You Tai, Matthew J. Betts, Janice M. Ranson, Margarita Zachariou, Olajide E. Olaleye, Saswati Das, Neil P. Oxtoby, Shanquan Chen, David J. Llewellyn, for the Deep Dementia Phenotyping (DEMON) Network
Format: Article
Language:English
Published: Wiley 2025-01-01
Series:Alzheimer’s & Dementia: Translational Research & Clinical Interventions
Subjects:
medications
drug repurposing
electronic health records
machine learning
pharmacoepidemiology
dementia
Online Access:https://doi.org/10.1002/trc2.70037
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