Zbtb7a is a transducer for the control of promoter accessibility by NF-kappa B and multiple other transcription factors.

Gene expression in eukaryotes is controlled by DNA sequences at promoter and enhancer regions, whose accessibility for binding by regulatory proteins dictates their specific patterns of activity. Here, we identify the protein Zbtb7a as a factor required for inducible changes in accessibility driven...

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Bibliographic Details
Main Authors: José Miguel Ramos Pittol, Agata Oruba, Gerhard Mittler, Simona Saccani, Dominic van Essen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-05-01
Series:PLoS Biology
Online Access:https://journals.plos.org/plosbiology/article/file?id=10.1371/journal.pbio.2004526&type=printable
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