Protective Action of 3,5-Diiodo-L-Thyronine on Cigarette Smoke-Induced Mitochondrial Dysfunction in Human Alveolar Epithelial Cells

Protective Action of 3,5-Diiodo-L-Thyronine on Cigarette Smoke-Induced Mitochondrial Dysfunction in Human Alveolar Epithelial Cells

<b>Background</b>: Cigarette smoke (CS) is a major risk factor for chronic lung conditions. Oxidative stress and mitochondrial dysfunction play a crucial role in CS-induced pulmonary injury. 3,5-Diiodothyronine (T2) affects energy metabolism, having mitochondria as a major target. Howeve...

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Bibliographic Details
Main Authors: Francesca Panico, Davida Mirra, Giuseppe Petito, Giuseppe Spaziano, Vitale Del Vecchio, Renata Esposito, Rosalba Senese, Vincenzo Desiderio, Antonia Lanni, Bruno D’Agostino
Format: Article
Language:English
Published: MDPI AG 2025-04-01
Series:Biomedicines
Subjects:
cigarette smoke
mitochondrial dysfunction
3,5-diiodo-L-thyronine
alveolar epithelial cells
oxidative stress
Online Access:https://www.mdpi.com/2227-9059/13/5/1014
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