Image guided construction of a common coordinate framework for spatial transcriptome data

Abstract Spatial transcriptomics is a powerful technology for high-resolution mapping of gene expression in tissue samples, enabling a molecular level understanding of tissue architecture. The acquisition entails dissecting and profiling micron-thick tissue slices, with multiple slices often needed...

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Bibliographic Details
Main Authors: Peter Lais, Shawn Mishra, Kun Xiong, Huanan Shi, Gurinder Singh Atwal, Yu Bai
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-025-01862-x
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