Photothermal and magnetic studies of Ni@Au nanotubes for anti-cancer therapies
Anisotropic ferromagnetic micro- and nanoparticles made of 3d metals demonstrate the ability to effectively influence micro- and nanoscale biological entities through hyperthermia and mechanical vibrations induced by magnetic fields. Multifunctional nanoparticles designed for combined therapies are...
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| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Pensoft Publishers
2025-06-01
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| Series: | Modern Electronic Materials |
| Online Access: | https://moem.pensoft.net/article/143172/download/pdf/ |
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| _version_ | 1850097513390931968 |
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| author | Anton Anikin Alena Shumskaya Anna Motorzhina Anastasia Gurevich Sergey Bedin Ilia Doludenko Dinara Khairetdinova Victor Belyaev Kateryna Levada Valeria Rodionova Larissa Panina |
| author_facet | Anton Anikin Alena Shumskaya Anna Motorzhina Anastasia Gurevich Sergey Bedin Ilia Doludenko Dinara Khairetdinova Victor Belyaev Kateryna Levada Valeria Rodionova Larissa Panina |
| author_sort | Anton Anikin |
| collection | DOAJ |
| description | Anisotropic ferromagnetic micro- and nanoparticles made of 3d metals demonstrate the ability to effectively influence micro- and nanoscale biological entities through hyperthermia and mechanical vibrations induced by magnetic fields. Multifunctional nanoparticles designed for combined therapies are particularly effective. This study explores the potential application of Ni@Au nanotubes to synergize magnetomechanical effects with photothermal heating. The orientation of nanotubes in a magnetic field was demonstrated by changes in the intensity of the light beam passing through a water suspension of nanotubes. The gold coating doubled the optical absorption of the solution in comparison with pure nickel nanotubes and resulted in the appearance of a resonance-enhanced peak in the range of 700–800 nm, the position of which is in accordance with theoretical calculations. The photothermal performance of nanotube solu-tions was quantitatively assessed by determining the photothermal conversion coefficient, which increased due to gold coating. However, it’s worth noting that the gold coating did not significantly reduce nanotube cytotoxicity in hepatocyte-derived cellular carcinoma cells (Huh7). The potential reasons for this outcome include the large particle size and non-uniform gold coating. Nevertheless, the combination of two anti-cancer therapies employing the same type of particles offers the opportunity to reduce particle concentration while maintaining the required therapeutic efficacy. |
| format | Article |
| id | doaj-art-ff97c48d9aa54f93940cf0485d998f94 |
| institution | DOAJ |
| issn | 2452-1779 |
| language | English |
| publishDate | 2025-06-01 |
| publisher | Pensoft Publishers |
| record_format | Article |
| series | Modern Electronic Materials |
| spelling | doaj-art-ff97c48d9aa54f93940cf0485d998f942025-08-20T02:40:56ZengPensoft PublishersModern Electronic Materials2452-17792025-06-01112819110.3897/j.moem.11.2.143172143172Photothermal and magnetic studies of Ni@Au nanotubes for anti-cancer therapiesAnton Anikin0Alena Shumskaya1Anna Motorzhina2Anastasia Gurevich3Sergey Bedin4Ilia Doludenko5Dinara Khairetdinova6Victor Belyaev7Kateryna Levada8Valeria Rodionova9Larissa Panina10Immanuel Kant Baltic Federal UniversityInstitute of Chemistry of New Materials of the National Academy of Sciences of BelarusImmanuel Kant Baltic Federal UniversityNational University of Science and Technology "MISIS"A.V. Shubnikov Institute of CrystallographyA.V. Shubnikov Institute of CrystallographyNational University of Science and Technology "MISIS"Immanuel Kant Baltic Federal UniversityImmanuel Kant Baltic Federal UniversityImmanuel Kant Baltic Federal UniversityNational University of Science and Technology "MISIS"Anisotropic ferromagnetic micro- and nanoparticles made of 3d metals demonstrate the ability to effectively influence micro- and nanoscale biological entities through hyperthermia and mechanical vibrations induced by magnetic fields. Multifunctional nanoparticles designed for combined therapies are particularly effective. This study explores the potential application of Ni@Au nanotubes to synergize magnetomechanical effects with photothermal heating. The orientation of nanotubes in a magnetic field was demonstrated by changes in the intensity of the light beam passing through a water suspension of nanotubes. The gold coating doubled the optical absorption of the solution in comparison with pure nickel nanotubes and resulted in the appearance of a resonance-enhanced peak in the range of 700–800 nm, the position of which is in accordance with theoretical calculations. The photothermal performance of nanotube solu-tions was quantitatively assessed by determining the photothermal conversion coefficient, which increased due to gold coating. However, it’s worth noting that the gold coating did not significantly reduce nanotube cytotoxicity in hepatocyte-derived cellular carcinoma cells (Huh7). The potential reasons for this outcome include the large particle size and non-uniform gold coating. Nevertheless, the combination of two anti-cancer therapies employing the same type of particles offers the opportunity to reduce particle concentration while maintaining the required therapeutic efficacy.https://moem.pensoft.net/article/143172/download/pdf/ |
| spellingShingle | Anton Anikin Alena Shumskaya Anna Motorzhina Anastasia Gurevich Sergey Bedin Ilia Doludenko Dinara Khairetdinova Victor Belyaev Kateryna Levada Valeria Rodionova Larissa Panina Photothermal and magnetic studies of Ni@Au nanotubes for anti-cancer therapies Modern Electronic Materials |
| title | Photothermal and magnetic studies of Ni@Au nanotubes for anti-cancer therapies |
| title_full | Photothermal and magnetic studies of Ni@Au nanotubes for anti-cancer therapies |
| title_fullStr | Photothermal and magnetic studies of Ni@Au nanotubes for anti-cancer therapies |
| title_full_unstemmed | Photothermal and magnetic studies of Ni@Au nanotubes for anti-cancer therapies |
| title_short | Photothermal and magnetic studies of Ni@Au nanotubes for anti-cancer therapies |
| title_sort | photothermal and magnetic studies of ni au nanotubes for anti cancer therapies |
| url | https://moem.pensoft.net/article/143172/download/pdf/ |
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