Melanocortin 1 Receptor Regulates Pathological and Physiological Cardiac Remodeling

Melanocortin 1 Receptor Regulates Pathological and Physiological Cardiac Remodeling

Background The melanocortin 1 receptor (MC1R) is abundantly expressed in the skin and leukocytes, where it regulates skin pigmentation and inflammatory responses. Recently, MC1R was also found in the heart, but its functional role has remained unknown. We aimed to investigate whether MC1R is involve...

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Bibliographic Details
Main Authors: Anni Suominen, Aino Suni, Saku Ruohonen, Zoltán Szabó, Lotta Pohjolainen, Minying Cai, Eriika Savontaus, Virpi Talman, Risto Kerkelä, Petteri Rinne
Format: Article
Language:English
Published: Wiley 2025-02-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
cardiac hypertrophy
cardiomyocyte
heart failure
melanocortin 1 receptor
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.124.037961
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