Posttransplant cyclophosphamide as GVHD prophylaxis in patients receiving mismatched unrelated HCT: the PHYLOS trial

Posttransplant cyclophosphamide as GVHD prophylaxis in patients receiving mismatched unrelated HCT: the PHYLOS trial

Abstract: Posttransplant high-dose cyclophosphamide (PTCy) is effective in overcoming the negative impact of HLA disparity in the haploidentical setting. In light of these results, we investigated the efficacy of PTCy, in improving clinical outcomes of hematopoietic stem cell transplantation (HSCT)...

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Main Authors: Anna Maria Raiola, Benedetto Bruno, Antonio Maria Risitano, Federico Mosna, Irene Maria Cavattoni, Francesco Onida, Giorgia Saporiti, Francesca Patriarca, Marta Lisa Battista, Vincenzo Pavone, Anna Mele, Patrizia Chiusolo, Simona Sica, Barbara Loteta, Carmen di Grazia, Angelo Michele Carella, Dalila Salvatore, Enrico Morello, Alessandro Leoni, Luisa Giaccone, Paolo Bernasconi, Elisabetta Terruzzi, Nicola Mordini, Carlo Borghero, Francesco Zallio, Mario Luppi, Anna Grassi, Attilio Olivieri, Eugenia Piras, Nicoletta Sacchi, Giovannino Ciccone, Anna Castiglione, Eliana Degrandi, Emanuele Angelucci, Massimo Martino, Francesca Bonifazi
Format: Article
Language:English
Published: Elsevier 2025-04-01
Series:Blood Advances
Online Access:http://www.sciencedirect.com/science/article/pii/S2473952925000941
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