DrFARM: identification of pleiotropic genetic variants in genome-wide association studies
Abstract In a standard analysis, pleiotropic variants are identified by running separate genome-wide association studies (GWAS) and combining results across traits. But such statistical approach based on marginal summary statistics may lead to spurious results. We propose a new statistical approach,...
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| Main Authors: | Lap Sum Chan, Gen Li, Eric B. Fauman, Xianyong Yin, Markku Laakso, Michael Boehnke, Peter X. K. Song |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-07-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-025-60439-4 |
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