Feline Calicivirus: A comprehensive review
A highly mutated RNA virus known as feline Kalisi virus (FCV) is commonly found in domestic cats. However, its potential for transmission to humans is minimal. FCV has significant genetic and antigenic diversity in cat populations. Severe acute systemic FCV infection (VS-FCV) manifests itself as lin...
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| Format: | Article |
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College of Veterinary Medicine, University of Basrah, Iraq
2025-06-01
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| Series: | Basrah Journal of Veterinary Research |
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| Online Access: | https://bjvr.uobasrah.edu.iq/article_188644_eca3008caee52b957f0038b711acebe0.pdf |
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| _version_ | 1849716127098208256 |
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| author | Hardi Marif Hana raoof kwestan Ali saman muhamad Basim Ali Rizgar Sulaiman othman nasrullah |
| author_facet | Hardi Marif Hana raoof kwestan Ali saman muhamad Basim Ali Rizgar Sulaiman othman nasrullah |
| author_sort | Hardi Marif |
| collection | DOAJ |
| description | A highly mutated RNA virus known as feline Kalisi virus (FCV) is commonly found in domestic cats. However, its potential for transmission to humans is minimal. FCV has significant genetic and antigenic diversity in cat populations. Severe acute systemic FCV infection (VS-FCV) manifests itself as lingual ulcers for upper respiratory tract diseases, gingivitis, alopecia, skin, mouth, ear problems, and claudication syndrome. Other symptoms include necrosis of the pancreas, liver, and spleen, bronchointerstitial pneumonia, and subcutaneous edema that contribute to the high mortality rate of infected cats. The diagnosis of FC virus is carried out using two techniques: reverse transcription-polymerase chain reaction (RT-PCR) and virus isolation. The frequency of antibodies is usually high in cat populations due to vaccination and symptomatic diseases. Therefore, the presence of certain antibodies does not always indicate the presence of a prolonged infection. The mainstay of FCV treatment is supportive care, although there are no authorized antiviral drugs specifically designed for the virus. However, drugs such as misuripine and nitazoxanide have proven their antiviral effectiveness in the laboratory. The types of vaccines available include inactivated and modified vaccines. Vaccination is necessary for the prevention of FCV virus. Preventing the spread of FCV requires proper hygiene and effective disinfection, especially in versatile environments. |
| format | Article |
| id | doaj-art-ff82bb21c1c748a1baa17dfb5eedf9b8 |
| institution | DOAJ |
| issn | 1813-8497 2410-8456 |
| language | English |
| publishDate | 2025-06-01 |
| publisher | College of Veterinary Medicine, University of Basrah, Iraq |
| record_format | Article |
| series | Basrah Journal of Veterinary Research |
| spelling | doaj-art-ff82bb21c1c748a1baa17dfb5eedf9b82025-08-20T03:13:07ZengCollege of Veterinary Medicine, University of Basrah, IraqBasrah Journal of Veterinary Research1813-84972410-84562025-06-0124214116510.23975/bjvr.2025.158296.1207188644Feline Calicivirus: A comprehensive reviewHardi Marif0Hana raoof1kwestan Ali2saman muhamad3Basim Ali4Rizgar Sulaiman5othman nasrullah6University of SulaimaniDepartment of Clinic and Internal Medicine/ College of Veterinary Medicine, University of SulaimaniDepartment of Clinic and Internal Medicine/ College of Veterinary Medicine, University of SulaimaniSulaimani veterinary DirectorateDepartment of Clinic and Internal Medicine/ College of Veterinary Medicine, University of SulaimaniDepartment of Clinic and Internal Medicine/ College of Veterinary Medicine, University of SulaimaniDepartment of Clinic and Internal Medicine/ College of Veterinary Medicine, University of SulaimaniA highly mutated RNA virus known as feline Kalisi virus (FCV) is commonly found in domestic cats. However, its potential for transmission to humans is minimal. FCV has significant genetic and antigenic diversity in cat populations. Severe acute systemic FCV infection (VS-FCV) manifests itself as lingual ulcers for upper respiratory tract diseases, gingivitis, alopecia, skin, mouth, ear problems, and claudication syndrome. Other symptoms include necrosis of the pancreas, liver, and spleen, bronchointerstitial pneumonia, and subcutaneous edema that contribute to the high mortality rate of infected cats. The diagnosis of FC virus is carried out using two techniques: reverse transcription-polymerase chain reaction (RT-PCR) and virus isolation. The frequency of antibodies is usually high in cat populations due to vaccination and symptomatic diseases. Therefore, the presence of certain antibodies does not always indicate the presence of a prolonged infection. The mainstay of FCV treatment is supportive care, although there are no authorized antiviral drugs specifically designed for the virus. However, drugs such as misuripine and nitazoxanide have proven their antiviral effectiveness in the laboratory. The types of vaccines available include inactivated and modified vaccines. Vaccination is necessary for the prevention of FCV virus. Preventing the spread of FCV requires proper hygiene and effective disinfection, especially in versatile environments.https://bjvr.uobasrah.edu.iq/article_188644_eca3008caee52b957f0038b711acebe0.pdfcaliciviruscatulcerationgingivostomatitis |
| spellingShingle | Hardi Marif Hana raoof kwestan Ali saman muhamad Basim Ali Rizgar Sulaiman othman nasrullah Feline Calicivirus: A comprehensive review Basrah Journal of Veterinary Research calicivirus cat ulceration gingivostomatitis |
| title | Feline Calicivirus: A comprehensive review |
| title_full | Feline Calicivirus: A comprehensive review |
| title_fullStr | Feline Calicivirus: A comprehensive review |
| title_full_unstemmed | Feline Calicivirus: A comprehensive review |
| title_short | Feline Calicivirus: A comprehensive review |
| title_sort | feline calicivirus a comprehensive review |
| topic | calicivirus cat ulceration gingivostomatitis |
| url | https://bjvr.uobasrah.edu.iq/article_188644_eca3008caee52b957f0038b711acebe0.pdf |
| work_keys_str_mv | AT hardimarif felinecalicivirusacomprehensivereview AT hanaraoof felinecalicivirusacomprehensivereview AT kwestanali felinecalicivirusacomprehensivereview AT samanmuhamad felinecalicivirusacomprehensivereview AT basimali felinecalicivirusacomprehensivereview AT rizgarsulaiman felinecalicivirusacomprehensivereview AT othmannasrullah felinecalicivirusacomprehensivereview |