Light-based therapies and radiodermatitis
The main treatments for cancer are radiotherapy and chemotherapy, but they can generate side effects such as fatigue, myelosuppression, and radiodermatitis. The Multinational Association of Supportive Care in Cancer already recommends the use of laser for radiodermatitis in breast cancer patients. H...
Saved in:
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
IfADo - Leibniz Research Centre for Working Environment and Human Factors, Dortmund
2024-10-01
|
| Series: | EXCLI Journal : Experimental and Clinical Sciences |
| Subjects: | |
| Online Access: | https://www.excli.de/excli/article/view/7749 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850059026931384320 |
|---|---|
| author | Talita Oliveira de Lima Karina Alexandra Batista da Silva Freitas Karen Aline Batista da Silva Maria Fernanda Setúbal Destro Rodrigues Thais Barbosa dos Santos Illora Aswinkumar Darbar Shimozato Christiane Pavani Rebeca Boltes Cecatto |
| author_facet | Talita Oliveira de Lima Karina Alexandra Batista da Silva Freitas Karen Aline Batista da Silva Maria Fernanda Setúbal Destro Rodrigues Thais Barbosa dos Santos Illora Aswinkumar Darbar Shimozato Christiane Pavani Rebeca Boltes Cecatto |
| author_sort | Talita Oliveira de Lima |
| collection | DOAJ |
| description | The main treatments for cancer are radiotherapy and chemotherapy, but they can generate side effects such as fatigue, myelosuppression, and radiodermatitis. The Multinational Association of Supportive Care in Cancer already recommends the use of laser for radiodermatitis in breast cancer patients. However, in relation to head and neck cancer patients, there is a lack of studies clearly demonstrating clinical effects and identifying the best light parameters for the treatment of radiodermatitis. This study reports on three oncological patients with radiodermatitis treated with light-based therapies to show clinical improvements in lesion grades and to discuss the effects of laser and its parameters. A retrospective report of three head and neck cancer patients with radiodermatitis, treated with photobiomodulation and photodynamic therapy at an outpatient health clinical facility. The Visual Analog Scale, Toxicity Criteria of the Radiation Therapy Oncology Group (RTOG) Scale, and the clinical characteristics of lesions were evaluated before and after a photobiomodulation plus photodynamic therapy protocol. Improvements were observed in cases with RTOG grade III with just 4 treatment sessions required for complete healing of the lesions. The patient with RTOG grade IV required antibiotic therapy, temporary suspension of radiotherapy, and more than 4 light sessions to achieve improvements. None of the patients showed worsening of the lesions, necrosis, or infection after treatment with no adverse effects. Head and neck cancer patients with radiodermatitis treated with phototherapy obtained good results in wound healing and pain relief in a short period. These case reports embody the easy-to-apply implementation of a light protocol in a health facility based on previous scientific evidence with positive results and no short-term side effects. In light of the negative impact on quality of life caused by radiodermatitis, health teams should be encouraged to design research study protocols involving light-based therapies. |
| format | Article |
| id | doaj-art-ff7f6b9a18f6436bb394c998bca0fa12 |
| institution | DOAJ |
| issn | 1611-2156 |
| language | English |
| publishDate | 2024-10-01 |
| publisher | IfADo - Leibniz Research Centre for Working Environment and Human Factors, Dortmund |
| record_format | Article |
| series | EXCLI Journal : Experimental and Clinical Sciences |
| spelling | doaj-art-ff7f6b9a18f6436bb394c998bca0fa122025-08-20T02:50:59ZengIfADo - Leibniz Research Centre for Working Environment and Human Factors, DortmundEXCLI Journal : Experimental and Clinical Sciences1611-21562024-10-01231276128610.17179/excli2024-77497188Light-based therapies and radiodermatitisTalita Oliveira de Lima0https://orcid.org/0000-0002-6617-6514Karina Alexandra Batista da Silva Freitas1https://orcid.org/0000-0002-3413-8468Karen Aline Batista da Silva2https://orcid.org/0000-0002-8643-5333Maria Fernanda Setúbal Destro Rodrigues3https://orcid.org/0000-0002-3067-9224Thais Barbosa dos Santos4https://orcid.org/0000-0001-6715-693XIllora Aswinkumar Darbar Shimozato5https://orcid.org/0000-0001-7208-2381Christiane Pavani6https://orcid.org/0000-0001-8275-7370Rebeca Boltes Cecatto7https://orcid.org/0000-0001-5675-6665Biophotonics-Medicine Post-Graduate Program / Universidade Nove de Julho UNINOVE, Rua Vergueiro 235, São Paulo, 01504-001, Brazil; Hospital das Clínicas da Faculdade de Medicina de Botucatu da Universidade Estadual Paulista (HCFMB-UNESP), São Paulo, 18618-687, BrazilHospital das Clínicas da Faculdade de Medicina de Botucatu da Universidade Estadual Paulista (HCFMB-UNESP), São Paulo, 18618-687, BrazilHospital das Clínicas da Faculdade de Medicina de Botucatu da Universidade Estadual Paulista (HCFMB-UNESP), São Paulo, 18618-687, BrazilBiophotonics-Medicine Post-Graduate Program / Universidade Nove de Julho UNINOVE, Rua Vergueiro 235, São Paulo, 01504-001, BrazilBiophotonics-Medicine Post-Graduate Program / Universidade Nove de Julho UNINOVE, Rua Vergueiro 235, São Paulo, 01504-001, BrazilBiophotonics-Medicine Post-Graduate Program / Universidade Nove de Julho UNINOVE, Rua Vergueiro 235, São Paulo, 01504-001, BrazilBiophotonics-Medicine Post-Graduate Program / Universidade Nove de Julho UNINOVE, Rua Vergueiro 235, São Paulo, 01504-001, BrazilBiophotonics-Medicine Post-Graduate Program / Universidade Nove de Julho UNINOVE, Rua Vergueiro 235, São Paulo, 01504-001, Brazil. Tel.: +55 11 970842496. E-mail: rebeca.boltes@gmail.com; rebeca.boltes@uni9.pro.brThe main treatments for cancer are radiotherapy and chemotherapy, but they can generate side effects such as fatigue, myelosuppression, and radiodermatitis. The Multinational Association of Supportive Care in Cancer already recommends the use of laser for radiodermatitis in breast cancer patients. However, in relation to head and neck cancer patients, there is a lack of studies clearly demonstrating clinical effects and identifying the best light parameters for the treatment of radiodermatitis. This study reports on three oncological patients with radiodermatitis treated with light-based therapies to show clinical improvements in lesion grades and to discuss the effects of laser and its parameters. A retrospective report of three head and neck cancer patients with radiodermatitis, treated with photobiomodulation and photodynamic therapy at an outpatient health clinical facility. The Visual Analog Scale, Toxicity Criteria of the Radiation Therapy Oncology Group (RTOG) Scale, and the clinical characteristics of lesions were evaluated before and after a photobiomodulation plus photodynamic therapy protocol. Improvements were observed in cases with RTOG grade III with just 4 treatment sessions required for complete healing of the lesions. The patient with RTOG grade IV required antibiotic therapy, temporary suspension of radiotherapy, and more than 4 light sessions to achieve improvements. None of the patients showed worsening of the lesions, necrosis, or infection after treatment with no adverse effects. Head and neck cancer patients with radiodermatitis treated with phototherapy obtained good results in wound healing and pain relief in a short period. These case reports embody the easy-to-apply implementation of a light protocol in a health facility based on previous scientific evidence with positive results and no short-term side effects. In light of the negative impact on quality of life caused by radiodermatitis, health teams should be encouraged to design research study protocols involving light-based therapies.https://www.excli.de/excli/article/view/7749photobiomodulationradiodermatitisphotodynamic therapyradiotherapycase reporthead and neck cancer |
| spellingShingle | Talita Oliveira de Lima Karina Alexandra Batista da Silva Freitas Karen Aline Batista da Silva Maria Fernanda Setúbal Destro Rodrigues Thais Barbosa dos Santos Illora Aswinkumar Darbar Shimozato Christiane Pavani Rebeca Boltes Cecatto Light-based therapies and radiodermatitis EXCLI Journal : Experimental and Clinical Sciences photobiomodulation radiodermatitis photodynamic therapy radiotherapy case report head and neck cancer |
| title | Light-based therapies and radiodermatitis |
| title_full | Light-based therapies and radiodermatitis |
| title_fullStr | Light-based therapies and radiodermatitis |
| title_full_unstemmed | Light-based therapies and radiodermatitis |
| title_short | Light-based therapies and radiodermatitis |
| title_sort | light based therapies and radiodermatitis |
| topic | photobiomodulation radiodermatitis photodynamic therapy radiotherapy case report head and neck cancer |
| url | https://www.excli.de/excli/article/view/7749 |
| work_keys_str_mv | AT talitaoliveiradelima lightbasedtherapiesandradiodermatitis AT karinaalexandrabatistadasilvafreitas lightbasedtherapiesandradiodermatitis AT karenalinebatistadasilva lightbasedtherapiesandradiodermatitis AT mariafernandasetubaldestrorodrigues lightbasedtherapiesandradiodermatitis AT thaisbarbosadossantos lightbasedtherapiesandradiodermatitis AT illoraaswinkumardarbarshimozato lightbasedtherapiesandradiodermatitis AT christianepavani lightbasedtherapiesandradiodermatitis AT rebecaboltescecatto lightbasedtherapiesandradiodermatitis |