LIMITED JOINT MOBILITY SYNDROME IN DIABETES MELLITUS

Patients with diabetes mellitus (DM) often show changes in the locomotor apparatus (LMA), in particular cheiroarthropathy, a specific lesion of the connective tissue structures of the hand in the presence of persistent hyperglycemia, which leads to limited joint mobility (LJM) generally in the absen...

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Main Authors: T. S. Panevin, L. I. Alekseeva, G. A. Melnichenko
Format: Article
Language:Russian
Published: IMA PRESS LLC 2020-06-01
Series:Научно-практическая ревматология
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Online Access:https://rsp.mediar-press.net/rsp/article/view/2901
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author T. S. Panevin
L. I. Alekseeva
G. A. Melnichenko
author_facet T. S. Panevin
L. I. Alekseeva
G. A. Melnichenko
author_sort T. S. Panevin
collection DOAJ
description Patients with diabetes mellitus (DM) often show changes in the locomotor apparatus (LMA), in particular cheiroarthropathy, a specific lesion of the connective tissue structures of the hand in the presence of persistent hyperglycemia, which leads to limited joint mobility (LJM) generally in the absence of pain syndrome. Some authors use the term «LJM syndrome» to describe LMA lesion in DM, since in the long course of the disease, the small and large joints of not only the upper, but also the lower limbs are involved in the pathological process. LJM is one of the little studied and poorly diagnosed conditions in comparison with traditional micro- and macro-vascular complications of DM, which, due to their direct correlation with life expectancy, receive more attention. The LJM syndrome is associated with other late complications of DM and can significantly impair functional activity, self-care, and quality of life. Damages to periarticular tissue and joints in DM are believed to be caused by the accumulation of glycation end products. A clinical examination plays a key role in the diagnosis of cheiroarthropathy.
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spelling doaj-art-ff78be6cc2fe4b89b8afa0a106a8122b2025-08-20T02:55:17ZrusIMA PRESS LLCНаучно-практическая ревматология1995-44841995-44922020-06-0158333033510.14412/1995-4484-2020-330-3352621LIMITED JOINT MOBILITY SYNDROME IN DIABETES MELLITUST. S. Panevin0L. I. Alekseeva1G. A. Melnichenko2V.A. Nasonova Research Institute of Rheumatology; National Research Center of Endocrinology; Consulting and Diagnostic Center, General Staff of the Armed Forces of the Russian FederationV.A. Nasonova Research Institute of RheumatologyNational Research Center of EndocrinologyPatients with diabetes mellitus (DM) often show changes in the locomotor apparatus (LMA), in particular cheiroarthropathy, a specific lesion of the connective tissue structures of the hand in the presence of persistent hyperglycemia, which leads to limited joint mobility (LJM) generally in the absence of pain syndrome. Some authors use the term «LJM syndrome» to describe LMA lesion in DM, since in the long course of the disease, the small and large joints of not only the upper, but also the lower limbs are involved in the pathological process. LJM is one of the little studied and poorly diagnosed conditions in comparison with traditional micro- and macro-vascular complications of DM, which, due to their direct correlation with life expectancy, receive more attention. The LJM syndrome is associated with other late complications of DM and can significantly impair functional activity, self-care, and quality of life. Damages to periarticular tissue and joints in DM are believed to be caused by the accumulation of glycation end products. A clinical examination plays a key role in the diagnosis of cheiroarthropathy.https://rsp.mediar-press.net/rsp/article/view/2901diabetes mellituscheiroarthropathyglycation end productslimited joint mobility syndromediabetic footpolyneuropathycomplications of diabetes mellitus
spellingShingle T. S. Panevin
L. I. Alekseeva
G. A. Melnichenko
LIMITED JOINT MOBILITY SYNDROME IN DIABETES MELLITUS
Научно-практическая ревматология
diabetes mellitus
cheiroarthropathy
glycation end products
limited joint mobility syndrome
diabetic foot
polyneuropathy
complications of diabetes mellitus
title LIMITED JOINT MOBILITY SYNDROME IN DIABETES MELLITUS
title_full LIMITED JOINT MOBILITY SYNDROME IN DIABETES MELLITUS
title_fullStr LIMITED JOINT MOBILITY SYNDROME IN DIABETES MELLITUS
title_full_unstemmed LIMITED JOINT MOBILITY SYNDROME IN DIABETES MELLITUS
title_short LIMITED JOINT MOBILITY SYNDROME IN DIABETES MELLITUS
title_sort limited joint mobility syndrome in diabetes mellitus
topic diabetes mellitus
cheiroarthropathy
glycation end products
limited joint mobility syndrome
diabetic foot
polyneuropathy
complications of diabetes mellitus
url https://rsp.mediar-press.net/rsp/article/view/2901
work_keys_str_mv AT tspanevin limitedjointmobilitysyndromeindiabetesmellitus
AT lialekseeva limitedjointmobilitysyndromeindiabetesmellitus
AT gamelnichenko limitedjointmobilitysyndromeindiabetesmellitus