Genetic aspects of non-alcoholic fatty liver disease development
Progression of non-alcoholic fatty liver disease (NAFLD) is conditioned by genetic susceptibility, environmental factors, lifestyle and features of the metabolic syndrome, many of which overlap with hepatocellular carcinoma. However, the multifactorial nature of NAFLD and the limited number of suffi...
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| Main Authors: | , |
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| Format: | Article |
| Language: | Russian |
| Published: |
Open Systems Publication
2021-06-01
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| Series: | Лечащий Врач |
| Subjects: | |
| Online Access: | https://journal.lvrach.ru/jour/article/view/316 |
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| Summary: | Progression of non-alcoholic fatty liver disease (NAFLD) is conditioned by genetic susceptibility, environmental factors, lifestyle and features of the metabolic syndrome, many of which overlap with hepatocellular carcinoma. However, the multifactorial nature of NAFLD and the limited number of sufficiently powerful studies are among the current limitations for validated biomarkers of clinical utility. Further studies incorporating the links between circadian regulation and hepatic metabolism may represent an additional direction in the search for predictive biomarkers of liver disease progression and treatment outcomes. |
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| ISSN: | 1560-5175 2687-1181 |