Tenascin C-Guided Nanosystem for Precision Delivery of Obeticholic Acid in Liver Fibrosis Therapy

Tenascin C-Guided Nanosystem for Precision Delivery of Obeticholic Acid in Liver Fibrosis Therapy

<b>Objective:</b> Liver fibrosis, a hallmark of chronic liver diseases, is characterized by excessive extracellular matrix (ECM) deposition and scar tissue formation. Current antifibrotic nanomedicines face significant limitations, including poor penetration into fibrotic tissue, rapid c...

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Bibliographic Details
Main Authors:	Yawen Wang, Lei Yang, Qing Xu, Taiyu Liu, Hongliang He, Lisha Liu, Lifang Yin
Format:	Article
Language:	English
Published:	MDPI AG 2024-12-01
Series:	Pharmaceutics
Subjects:	antifibrotic nanomedicine hepatic inflammation TnC-triggered sequential delivery obeticholic acid
Online Access:	https://www.mdpi.com/1999-4923/17/1/32
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