The diagnostic pitfalls of mucormycosis

Background Invasive mucormycosis is a very aggressive fungal disease among immunocompromised pediatric patients caused by saprophytic fungi that belong to the order of the Mucorales. Case Report We describe a case of  of Lichtheimia corymbifera infection in a 15-year-old child with B-cell Non-Hod...

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Main Authors: Margherita Mauro, Giuliana Lo Cascio, Rita Balter, Ada Zaccaron, Elisa Bonetti, Virgina Vitale, Matteo Chinello, Massimiliano De Bortoli, Paolo Brazzarola, Costanza Bruno, Simone Cesaro
Format: Article
Language:English
Published: PAGEPress Publications 2020-10-01
Series:Mediterranean Journal of Hematology and Infectious Diseases
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Online Access:http://www.mjhid.org/index.php/mjhid/article/view/4409
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Summary:Background Invasive mucormycosis is a very aggressive fungal disease among immunocompromised pediatric patients caused by saprophytic fungi that belong to the order of the Mucorales. Case Report We describe a case of  of Lichtheimia corymbifera infection in a 15-year-old child with B-cell Non-Hodgkin Lymphoma (NHL) involving lung, kidney and thyroid that initially was diagnosed as probable aspergillosis delaying the effective therapy for mucormycosis. Conclusions This case showed that also intensive chemotherapy with rituximab may represent a risk factor for mucormycosis infection. Liposomal amphotericin B and surgery  remain  key tools  for a successful treatment of this aggressive disease.
ISSN:2035-3006