Retrospective Case Reports of Anemic Pregnant Women Receiving Intravenous Ferric Carboxymaltose: Experience from a Tertiary Hospital in Spain
Iron deficiency and iron deficiency anemia during pregnancy call for safe treatment options that raise maternal hemoglobin levels and counterbalance iron demand and blood volume expansion while minimizing risks for the growing fetus. This retrospective study describes experience with intravenous fer...
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Wiley
2016-01-01
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| Series: | Obstetrics and Gynecology International |
| Online Access: | http://dx.doi.org/10.1155/2016/5060252 |
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| author | Rafael Aporta Rodriguez Mariola García Montero Jose Pablo Lorente Aporta Carolina Gallego Luque Alfonso Chacón Mayor Jose Aragón Ruiz Virginia Torres Degayón Claudia García Jimenez Guadalupe Sanchez Sanchez |
| author_facet | Rafael Aporta Rodriguez Mariola García Montero Jose Pablo Lorente Aporta Carolina Gallego Luque Alfonso Chacón Mayor Jose Aragón Ruiz Virginia Torres Degayón Claudia García Jimenez Guadalupe Sanchez Sanchez |
| author_sort | Rafael Aporta Rodriguez |
| collection | DOAJ |
| description | Iron deficiency and iron deficiency anemia during pregnancy call for safe treatment options that raise maternal hemoglobin levels and counterbalance iron demand and blood volume expansion while minimizing risks for the growing fetus. This retrospective study describes experience with intravenous ferric carboxymaltose given to pregnant women in a tertiary hospital in Spain. In a 5-year period, 95 pregnant women who had pretreatment hemoglobin <10 g/dL and at least one time of ferric carboxymaltose administration during pregnancy were included. Main outcome measures were week of pregnancy at iron administration, Hb levels before and after treatment, neonatal 5-minute Apgar scores, and birth weight. The majority received one dose of ferric carboxymaltose (1000 mg iron) during advanced pregnancy (median 31 weeks; interquartile range [IQR]: 27; 37 weeks) with minor to no adverse outcomes. Overall, median Hb increased from 8.5 g/dL (8.1; 8.9 g/dL) before treatment to 11.0 g/dL (9.9; 11.7 g/dL) after treatment. Normal Apgar scores were observed in all 97 infants (median birth weights 3560 g, 3270, and 3798 g). Four women received ferric carboxymaltose in the first trimester and twenty-eight during the second trimester without adverse outcomes for mother or child. These cases add to the evidence that ferric carboxymaltose administration during pregnancy is effective and safe. |
| format | Article |
| id | doaj-art-ff665969cc0346faa384b2b2c40f6bbf |
| institution | Kabale University |
| issn | 1687-9589 1687-9597 |
| language | English |
| publishDate | 2016-01-01 |
| publisher | Wiley |
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| series | Obstetrics and Gynecology International |
| spelling | doaj-art-ff665969cc0346faa384b2b2c40f6bbf2025-08-20T03:25:42ZengWileyObstetrics and Gynecology International1687-95891687-95972016-01-01201610.1155/2016/50602525060252Retrospective Case Reports of Anemic Pregnant Women Receiving Intravenous Ferric Carboxymaltose: Experience from a Tertiary Hospital in SpainRafael Aporta Rodriguez0Mariola García Montero1Jose Pablo Lorente Aporta2Carolina Gallego Luque3Alfonso Chacón Mayor4Jose Aragón Ruiz5Virginia Torres Degayón6Claudia García Jimenez7Guadalupe Sanchez Sanchez8Hematology Department, Hospital Universitario de Ceuta, Ceuta, SpainHematology Department, Hospital Universitario de Ceuta, Ceuta, SpainHematology Department, Hospital Universitario de Ceuta, Ceuta, SpainHematology Department, Hospital Universitario de Ceuta, Ceuta, SpainHematology Department, Hospital Universitario de Ceuta, Ceuta, SpainGynecology and Obstetrics Department, Hospital Universitario de Ceuta, Ceuta, SpainPharmacy Department, Hospital Universitario de Ceuta, Ceuta, SpainPharmacy Department, Hospital Universitario de Ceuta, Ceuta, SpainDermatology Department, Hospital Universitario de Ceuta, Ceuta, SpainIron deficiency and iron deficiency anemia during pregnancy call for safe treatment options that raise maternal hemoglobin levels and counterbalance iron demand and blood volume expansion while minimizing risks for the growing fetus. This retrospective study describes experience with intravenous ferric carboxymaltose given to pregnant women in a tertiary hospital in Spain. In a 5-year period, 95 pregnant women who had pretreatment hemoglobin <10 g/dL and at least one time of ferric carboxymaltose administration during pregnancy were included. Main outcome measures were week of pregnancy at iron administration, Hb levels before and after treatment, neonatal 5-minute Apgar scores, and birth weight. The majority received one dose of ferric carboxymaltose (1000 mg iron) during advanced pregnancy (median 31 weeks; interquartile range [IQR]: 27; 37 weeks) with minor to no adverse outcomes. Overall, median Hb increased from 8.5 g/dL (8.1; 8.9 g/dL) before treatment to 11.0 g/dL (9.9; 11.7 g/dL) after treatment. Normal Apgar scores were observed in all 97 infants (median birth weights 3560 g, 3270, and 3798 g). Four women received ferric carboxymaltose in the first trimester and twenty-eight during the second trimester without adverse outcomes for mother or child. These cases add to the evidence that ferric carboxymaltose administration during pregnancy is effective and safe.http://dx.doi.org/10.1155/2016/5060252 |
| spellingShingle | Rafael Aporta Rodriguez Mariola García Montero Jose Pablo Lorente Aporta Carolina Gallego Luque Alfonso Chacón Mayor Jose Aragón Ruiz Virginia Torres Degayón Claudia García Jimenez Guadalupe Sanchez Sanchez Retrospective Case Reports of Anemic Pregnant Women Receiving Intravenous Ferric Carboxymaltose: Experience from a Tertiary Hospital in Spain Obstetrics and Gynecology International |
| title | Retrospective Case Reports of Anemic Pregnant Women Receiving Intravenous Ferric Carboxymaltose: Experience from a Tertiary Hospital in Spain |
| title_full | Retrospective Case Reports of Anemic Pregnant Women Receiving Intravenous Ferric Carboxymaltose: Experience from a Tertiary Hospital in Spain |
| title_fullStr | Retrospective Case Reports of Anemic Pregnant Women Receiving Intravenous Ferric Carboxymaltose: Experience from a Tertiary Hospital in Spain |
| title_full_unstemmed | Retrospective Case Reports of Anemic Pregnant Women Receiving Intravenous Ferric Carboxymaltose: Experience from a Tertiary Hospital in Spain |
| title_short | Retrospective Case Reports of Anemic Pregnant Women Receiving Intravenous Ferric Carboxymaltose: Experience from a Tertiary Hospital in Spain |
| title_sort | retrospective case reports of anemic pregnant women receiving intravenous ferric carboxymaltose experience from a tertiary hospital in spain |
| url | http://dx.doi.org/10.1155/2016/5060252 |
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