Public perceptions and influencing factors of seasonal influenza vaccine uptake in Makkah region, Saudi Arabia: a cross-sectional study

BackgroundSeasonal influenza vaccination is essential for reducing the risk and impact of influenza. Makkah region in Saudi Arabia, a destination for millions of pilgrims during Hajj and Umrah, presents a unique context for this study. Therefore, this research investigates the prevalence and influen...

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Main Authors: Mohammed S. Alharthi, Abdullah A. Alshehri, Fahad H. Baali, Nawaf Awd Altuwairqi, Meshari Hassan Altalhi, Rayan Azib Almalki, Meshal Khalid Aljuaid, Majed A. Algarni, Mohmmed S. Alzahrani, Nasser M. Alorfi, Wadia S. Alruqayb
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-02-01
Series:Frontiers in Public Health
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Online Access:https://www.frontiersin.org/articles/10.3389/fpubh.2025.1534176/full
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author Mohammed S. Alharthi
Abdullah A. Alshehri
Fahad H. Baali
Nawaf Awd Altuwairqi
Meshari Hassan Altalhi
Rayan Azib Almalki
Meshal Khalid Aljuaid
Majed A. Algarni
Mohmmed S. Alzahrani
Nasser M. Alorfi
Wadia S. Alruqayb
author_facet Mohammed S. Alharthi
Abdullah A. Alshehri
Fahad H. Baali
Nawaf Awd Altuwairqi
Meshari Hassan Altalhi
Rayan Azib Almalki
Meshal Khalid Aljuaid
Majed A. Algarni
Mohmmed S. Alzahrani
Nasser M. Alorfi
Wadia S. Alruqayb
author_sort Mohammed S. Alharthi
collection DOAJ
description BackgroundSeasonal influenza vaccination is essential for reducing the risk and impact of influenza. Makkah region in Saudi Arabia, a destination for millions of pilgrims during Hajj and Umrah, presents a unique context for this study. Therefore, this research investigates the prevalence and influencing factors of influenza vaccine uptake among the public in Makkah region, Saudi Arabia.MethodThis cross-sectional study was conducted in Saudi Arabia between February and June 2024. The main researcher developed the questionnaire, which was reviewed by five academics and then piloted with 20 individuals for validation. An online questionnaire was used, targeting residents aged 18 and over with internet access. A snowball sampling method was applied. Data were collected via Google Forms and analyzed using SPSS version 26, employing descriptive statistics such as frequencies, percentages, and means.ResultsThe total number of respondents is 450 participants, with a response rate of 4.5%. Most respondents were male (71.1%) and aged between 18 and 30 years (44.5%). Education levels varied, with 57.5% holding a bachelor’s degree. Vaccination uptake showed 65.1% had received the vaccine, with 31.1% confident it is safe. Despite this, 58.8% did not get vaccinated this season. Confidence in the vaccine’s effectiveness was 59.5%, though 41.2% reported breakthrough infections. Accessibility was generally rated easy (57.7%). Social pressure (17.4%), trust in health institutions (36.9%), and COVID-19 concerns (36.7%) significantly influenced vaccination decisions. The likelihood of vaccination next season displayed polarized views.ConclusionThis study provides significant insights about vaccine hesitancy that may inform future research endeavors and practical applications. Understanding the various factors that impact the adoption of influenza vaccines offers valuable insights for developing targeted interventions and public health policies to improve vaccination rates. This study enhances theoretical understanding and practical strategies to encourage influenza vaccination, thereby improving public health initiatives in the area and beyond.
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spelling doaj-art-ff64b3a6af7d471782907dfdfa10bfec2025-08-20T02:43:55ZengFrontiers Media S.A.Frontiers in Public Health2296-25652025-02-011310.3389/fpubh.2025.15341761534176Public perceptions and influencing factors of seasonal influenza vaccine uptake in Makkah region, Saudi Arabia: a cross-sectional studyMohammed S. Alharthi0Abdullah A. Alshehri1Fahad H. Baali2Nawaf Awd Altuwairqi3Meshari Hassan Altalhi4Rayan Azib Almalki5Meshal Khalid Aljuaid6Majed A. Algarni7Mohmmed S. Alzahrani8Nasser M. Alorfi9Wadia S. Alruqayb10Department of Clinical Pharmacy, College of Pharmacy, Taif University, Taif, Saudi ArabiaDepartment of Clinical Pharmacy, College of Pharmacy, Taif University, Taif, Saudi ArabiaDepartment of Clinical Pharmacy, College of Pharmacy, Taif University, Taif, Saudi ArabiaDepartment of Clinical Pharmacy, College of Pharmacy, Taif University, Taif, Saudi ArabiaDepartment of Clinical Pharmacy, College of Pharmacy, Taif University, Taif, Saudi ArabiaDepartment of Clinical Pharmacy, College of Pharmacy, Taif University, Taif, Saudi ArabiaDepartment of Clinical Pharmacy, College of Pharmacy, Taif University, Taif, Saudi ArabiaDepartment of Clinical Pharmacy, College of Pharmacy, Taif University, Taif, Saudi ArabiaDepartment of Clinical Pharmacy, College of Pharmacy, Taif University, Taif, Saudi ArabiaDepartment of Pharmacology and Toxicology, College of Pharmacy, Umm Al-Qura University, Makkah, Saudi ArabiaDepartment of Clinical Pharmacy, College of Pharmacy, Taif University, Taif, Saudi ArabiaBackgroundSeasonal influenza vaccination is essential for reducing the risk and impact of influenza. Makkah region in Saudi Arabia, a destination for millions of pilgrims during Hajj and Umrah, presents a unique context for this study. Therefore, this research investigates the prevalence and influencing factors of influenza vaccine uptake among the public in Makkah region, Saudi Arabia.MethodThis cross-sectional study was conducted in Saudi Arabia between February and June 2024. The main researcher developed the questionnaire, which was reviewed by five academics and then piloted with 20 individuals for validation. An online questionnaire was used, targeting residents aged 18 and over with internet access. A snowball sampling method was applied. Data were collected via Google Forms and analyzed using SPSS version 26, employing descriptive statistics such as frequencies, percentages, and means.ResultsThe total number of respondents is 450 participants, with a response rate of 4.5%. Most respondents were male (71.1%) and aged between 18 and 30 years (44.5%). Education levels varied, with 57.5% holding a bachelor’s degree. Vaccination uptake showed 65.1% had received the vaccine, with 31.1% confident it is safe. Despite this, 58.8% did not get vaccinated this season. Confidence in the vaccine’s effectiveness was 59.5%, though 41.2% reported breakthrough infections. Accessibility was generally rated easy (57.7%). Social pressure (17.4%), trust in health institutions (36.9%), and COVID-19 concerns (36.7%) significantly influenced vaccination decisions. The likelihood of vaccination next season displayed polarized views.ConclusionThis study provides significant insights about vaccine hesitancy that may inform future research endeavors and practical applications. Understanding the various factors that impact the adoption of influenza vaccines offers valuable insights for developing targeted interventions and public health policies to improve vaccination rates. This study enhances theoretical understanding and practical strategies to encourage influenza vaccination, thereby improving public health initiatives in the area and beyond.https://www.frontiersin.org/articles/10.3389/fpubh.2025.1534176/fullseasonal influenza vaccineinfluenzahesitancypublicMakkah regionSaudi Arabia
spellingShingle Mohammed S. Alharthi
Abdullah A. Alshehri
Fahad H. Baali
Nawaf Awd Altuwairqi
Meshari Hassan Altalhi
Rayan Azib Almalki
Meshal Khalid Aljuaid
Majed A. Algarni
Mohmmed S. Alzahrani
Nasser M. Alorfi
Wadia S. Alruqayb
Public perceptions and influencing factors of seasonal influenza vaccine uptake in Makkah region, Saudi Arabia: a cross-sectional study
Frontiers in Public Health
seasonal influenza vaccine
influenza
hesitancy
public
Makkah region
Saudi Arabia
title Public perceptions and influencing factors of seasonal influenza vaccine uptake in Makkah region, Saudi Arabia: a cross-sectional study
title_full Public perceptions and influencing factors of seasonal influenza vaccine uptake in Makkah region, Saudi Arabia: a cross-sectional study
title_fullStr Public perceptions and influencing factors of seasonal influenza vaccine uptake in Makkah region, Saudi Arabia: a cross-sectional study
title_full_unstemmed Public perceptions and influencing factors of seasonal influenza vaccine uptake in Makkah region, Saudi Arabia: a cross-sectional study
title_short Public perceptions and influencing factors of seasonal influenza vaccine uptake in Makkah region, Saudi Arabia: a cross-sectional study
title_sort public perceptions and influencing factors of seasonal influenza vaccine uptake in makkah region saudi arabia a cross sectional study
topic seasonal influenza vaccine
influenza
hesitancy
public
Makkah region
Saudi Arabia
url https://www.frontiersin.org/articles/10.3389/fpubh.2025.1534176/full
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