Morphological vs. molecular identification of trematode species infecting the edible cockle Cerastoderma edule across Europe

Identifying marine trematode parasites in host tissue can be complicated when there is limited morphological differentiation between species infecting the same host species. This poses a challenge for regular surveys of the parasite communities in species of socio-economic and ecological importance....

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Main Authors: Leslie Stout, Guillemine Daffe, Aurélie Chambouvet, Simão Correia, Sarah Culloty, Rosa Freitas, David Iglesias, K. Thomas Jensen, Sandra Joaquim, Sharon Lynch, Luisa Magalhães, Kate Mahony, Shelagh K. Malham, Domitilia Matias, Mélanie Rocroy, David W. Thieltges, Xavier de Montaudouin
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:International Journal for Parasitology: Parasites and Wildlife
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Online Access:http://www.sciencedirect.com/science/article/pii/S2213224424001159
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author Leslie Stout
Guillemine Daffe
Aurélie Chambouvet
Simão Correia
Sarah Culloty
Rosa Freitas
David Iglesias
K. Thomas Jensen
Sandra Joaquim
Sharon Lynch
Luisa Magalhães
Kate Mahony
Shelagh K. Malham
Domitilia Matias
Mélanie Rocroy
David W. Thieltges
Xavier de Montaudouin
author_facet Leslie Stout
Guillemine Daffe
Aurélie Chambouvet
Simão Correia
Sarah Culloty
Rosa Freitas
David Iglesias
K. Thomas Jensen
Sandra Joaquim
Sharon Lynch
Luisa Magalhães
Kate Mahony
Shelagh K. Malham
Domitilia Matias
Mélanie Rocroy
David W. Thieltges
Xavier de Montaudouin
author_sort Leslie Stout
collection DOAJ
description Identifying marine trematode parasites in host tissue can be complicated when there is limited morphological differentiation between species infecting the same host species. This poses a challenge for regular surveys of the parasite communities in species of socio-economic and ecological importance. Our study focused on identifying digenean trematode species infecting the marine bivalve Cerastoderma edule across Europe by comparing morphological and molecular species identification methods. Cockles were sampled from ten locations to observe the trematode parasites under a stereomicroscope (morphological identification) and to isolate individuals for phylogenetic analyses using two gene markers, the small sub-unit ribosomal (18S) RNA gene (SSU rDNA) and the mitochondrial cytochrome c oxidase subunit 1 (cox1). For the first time, we compared both morphological identification and phylogenetic analyses for each of the 13 originally identified species. First, we identified a group of five species for which morphological identification matched molecular results (Bucephalus minimus, Monorchis parvus, Renicola parvicaudatus, Psilostomum brevicolle, Himasthla interrupta). Second, we identified a group of six species for which molecular results revealed either misidentifications or cryptic diversity (Gymnophallus choledochus, Diphterostomum brusinae, Curtuteria arguinae, Himasthla quissetensis, H. elongata, H. continua). Third, our analyses showed that all sequences of two expected species, Gymnophallus minutus and G. fossarum, matched between the two, strongly suggesting that only G. minutus is present in the studied area. Our study clearly demonstrates that molecular tools are necessary to validate the trematode species composition. However, with 17 distinct genetic lineages detected, some of which are not fully identified, future studies are needed to clarify the identity and status (regular vs. accidental infection) of some of these cryptic trematode species.
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spelling doaj-art-ff62a84b4ceb4f6bbe8bfd2832aeb5fb2025-08-20T02:39:27ZengElsevierInternational Journal for Parasitology: Parasites and Wildlife2213-22442024-12-012510101910.1016/j.ijppaw.2024.101019Morphological vs. molecular identification of trematode species infecting the edible cockle Cerastoderma edule across EuropeLeslie Stout0Guillemine Daffe1Aurélie Chambouvet2Simão Correia3Sarah Culloty4Rosa Freitas5David Iglesias6K. Thomas Jensen7Sandra Joaquim8Sharon Lynch9Luisa Magalhães10Kate Mahony11Shelagh K. Malham12Domitilia Matias13Mélanie Rocroy14David W. Thieltges15Xavier de Montaudouin16Univ. Bordeaux, CNRS, Bordeaux INP, EPOC, UMR, 5805, Station Marine d’Arcachon, Arcachon, France; Corresponding author.Univ. Bordeaux, CNRS, OASU, UAR, 2567, POREA, Pessac, FranceCNRS, UMR 7144 AD2M, Station Biologique de Roscoff, Sorbonne Université, Roscoff, FranceCESAM & Department of Biology, University of Aveiro, Campus Universitario de Santiago, 3810-193, Aveiro, PortugalSchool of Biological, Earth and Environmental Sciences and Aquaculture and Fisheries Development Centre, University College Cork, Cork, Ireland; Environmental Research Institute, University College Cork, Cork, Ireland; MaREI Centre, Environmental Research Institute, University College Cork, Cork, IrelandCESAM & Department of Biology, University of Aveiro, Campus Universitario de Santiago, 3810-193, Aveiro, PortugalCentro de Investigacións Mariñas (CIMA), Consellería do Mar, Xunta de Galicia, Vilanova de Arousa, SpainDepartment of Biology, Ole Worms Allé 1, Building 1134, 8000, Aarhus C, DenmarkDepartment of Sea and Marine Resources, Portuguese Institute for Sea and Atmosphere (IPMA, I.P.), Av. 5 de Outubro s/n, 8700-305, Olhão, Portugal; Interdisciplinary Centre of Marine Environmental Research (CIIMAR), University of Porto, Terminal de Cruzeiros do Porto de Leixões, Av. General Norton de Matos s/n, 4450-208, Matosinhos, PortugalSchool of Biological, Earth and Environmental Sciences and Aquaculture and Fisheries Development Centre, University College Cork, Cork, Ireland; Environmental Research Institute, University College Cork, Cork, IrelandCESAM & Department of Biology, University of Aveiro, Campus Universitario de Santiago, 3810-193, Aveiro, PortugalSchool of Biological, Earth and Environmental Sciences and Aquaculture and Fisheries Development Centre, University College Cork, Cork, Ireland; Environmental Research Institute, University College Cork, Cork, IrelandSchool of Ocean Sciences, Bangor University, Menai Bridge, Anglesey, LL59 5AB, United KingdomDepartment of Sea and Marine Resources, Portuguese Institute for Sea and Atmosphere (IPMA, I.P.), Av. 5 de Outubro s/n, 8700-305, Olhão, Portugal; Interdisciplinary Centre of Marine Environmental Research (CIIMAR), University of Porto, Terminal de Cruzeiros do Porto de Leixões, Av. General Norton de Matos s/n, 4450-208, Matosinhos, PortugalGEMEL- Groupe d'étude des Milieux Estuariens et Littoraux, Saint-Valery-sur-Somme, FranceDepartment of Coastal Systems, NIOZ Royal Netherlands Institute for Sea Research, Den Burg, Texel, the Netherlands; Groningen Institute for Evolutionary Life-Sciences (GELIFES), University of Groningen, Groningen, the NetherlandsUniv. Bordeaux, CNRS, Bordeaux INP, EPOC, UMR, 5805, Station Marine d’Arcachon, Arcachon, FranceIdentifying marine trematode parasites in host tissue can be complicated when there is limited morphological differentiation between species infecting the same host species. This poses a challenge for regular surveys of the parasite communities in species of socio-economic and ecological importance. Our study focused on identifying digenean trematode species infecting the marine bivalve Cerastoderma edule across Europe by comparing morphological and molecular species identification methods. Cockles were sampled from ten locations to observe the trematode parasites under a stereomicroscope (morphological identification) and to isolate individuals for phylogenetic analyses using two gene markers, the small sub-unit ribosomal (18S) RNA gene (SSU rDNA) and the mitochondrial cytochrome c oxidase subunit 1 (cox1). For the first time, we compared both morphological identification and phylogenetic analyses for each of the 13 originally identified species. First, we identified a group of five species for which morphological identification matched molecular results (Bucephalus minimus, Monorchis parvus, Renicola parvicaudatus, Psilostomum brevicolle, Himasthla interrupta). Second, we identified a group of six species for which molecular results revealed either misidentifications or cryptic diversity (Gymnophallus choledochus, Diphterostomum brusinae, Curtuteria arguinae, Himasthla quissetensis, H. elongata, H. continua). Third, our analyses showed that all sequences of two expected species, Gymnophallus minutus and G. fossarum, matched between the two, strongly suggesting that only G. minutus is present in the studied area. Our study clearly demonstrates that molecular tools are necessary to validate the trematode species composition. However, with 17 distinct genetic lineages detected, some of which are not fully identified, future studies are needed to clarify the identity and status (regular vs. accidental infection) of some of these cryptic trematode species.http://www.sciencedirect.com/science/article/pii/S2213224424001159Molecular taxonomyTrematodesCerastoderma eduleNorth-East Atlanticcox1SSU (18S) rRNA gene
spellingShingle Leslie Stout
Guillemine Daffe
Aurélie Chambouvet
Simão Correia
Sarah Culloty
Rosa Freitas
David Iglesias
K. Thomas Jensen
Sandra Joaquim
Sharon Lynch
Luisa Magalhães
Kate Mahony
Shelagh K. Malham
Domitilia Matias
Mélanie Rocroy
David W. Thieltges
Xavier de Montaudouin
Morphological vs. molecular identification of trematode species infecting the edible cockle Cerastoderma edule across Europe
International Journal for Parasitology: Parasites and Wildlife
Molecular taxonomy
Trematodes
Cerastoderma edule
North-East Atlantic
cox1
SSU (18S) rRNA gene
title Morphological vs. molecular identification of trematode species infecting the edible cockle Cerastoderma edule across Europe
title_full Morphological vs. molecular identification of trematode species infecting the edible cockle Cerastoderma edule across Europe
title_fullStr Morphological vs. molecular identification of trematode species infecting the edible cockle Cerastoderma edule across Europe
title_full_unstemmed Morphological vs. molecular identification of trematode species infecting the edible cockle Cerastoderma edule across Europe
title_short Morphological vs. molecular identification of trematode species infecting the edible cockle Cerastoderma edule across Europe
title_sort morphological vs molecular identification of trematode species infecting the edible cockle cerastoderma edule across europe
topic Molecular taxonomy
Trematodes
Cerastoderma edule
North-East Atlantic
cox1
SSU (18S) rRNA gene
url http://www.sciencedirect.com/science/article/pii/S2213224424001159
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