Near-infrared light activatable chemically induced CRISPR system
Abstract The biggest challenge in using CRISPR technologies, which limits their widespread application in medicine, is off-target effects. These effects could, in principle, be minimized by ensuring that CRISPR is activated primarily in the targeted cells, thereby reducing the likelihood of unintend...
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| Main Authors: | Lei Zhang, Xuejun Zhang, Le Qiu, Song Mao, Jia Sheng, Liming Chen, Umar Khan, Paul K. Upputuri, Yuri N. Zakharov, Mark F. Coughlan, Lev T. Perelman |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Publishing Group
2025-07-01
|
| Series: | Light: Science & Applications |
| Online Access: | https://doi.org/10.1038/s41377-025-01917-8 |
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