Promise and Peril of a Genotype‐First Approach to Mendelian Cardiovascular Disease

Promise and Peril of a Genotype‐First Approach to Mendelian Cardiovascular Disease

Precision medicine, which among other aspects includes an individual's genomic data in diagnosis and management, has become the standard‐of‐care for Mendelian cardiovascular disease (CVD). However, early identification and management of asymptomatic patients with potentially lethal and manageab...

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Main Authors: Babken Asatryan, Brittney Murray, Rafik Tadros, Marina Rieder, Ravi A. Shah, Ghaith Sharaf Dabbagh, Andrew P. Landstrom, Stephan Dobner, Patricia B. Munroe, Christopher M. Haggerty, Argelia Medeiros‐Domingo, Anjali T. Owens, Iftikhar J. Kullo, Christopher Semsarian, Tobias Reichlin, Andreas S. Barth, Dan M. Roden, Cynthia A. James, James S. Ware, C. Anwar A. Chahal
Format: Article
Language:English
Published: Wiley 2024-11-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
biobank
cardiac arrhythmia
cardiomyopathy
genetics
precision health
precision medicine sudden cardiac death
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.123.033557
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