Integrative analysis of polyamine metabolism-related genes in gliomas: implications for prognosis and therapy

Integrative analysis of polyamine metabolism-related genes in gliomas: implications for prognosis and therapy

IntroductionTumor transformation and progression are accompanied by multiple carcinogenic pathways that dysregulate polyamine demand and metabolism. The importance of polyamines has demonstrated that their metabolism is a potential therapeutic strategy. Yet, few prognostic models based on polyamine...

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Bibliographic Details
Main Authors:	Yujia Zhao, Zhenkai Fu, Sijie Chen, Fei Li, Xiaoyu Zhang, Kaidiriye Setiwalidi, Zhiping Ruan, Yu Yao, Lanxin Luo
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-07-01
Series:	Frontiers in Oncology
Subjects:	polyamine glioma prognosis immunosuppression spermine synthase
Online Access:	https://www.frontiersin.org/articles/10.3389/fonc.2025.1517557/full
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