Overview of distinct 8-oxoguanine profiles of messenger RNA in normal and senescent cancer cells

Overview of distinct 8-oxoguanine profiles of messenger RNA in normal and senescent cancer cells

BackgroundCellular senescence plays a key role in the development of cancer, but the underlying mechanisms are unknown. Recently, several recent studies have shown that RNA methylation is closely related to cancer cell aging. 8-Oxoguanine (o8G) is an important and widely distributed methylation modi...

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Bibliographic Details
Main Authors: Jingwen Huang, Yu Lin, Yingying Zhao, Lingbo Wei
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-02-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
8-oxoguanine
senescence
RNA methylation
MeRIP-seq
cancer cell
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2025.1443888/full
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