Programmable production of bioactive extracellular vesicles in vivo to treat myocardial infarction

Programmable production of bioactive extracellular vesicles in vivo to treat myocardial infarction

Abstract Current myocardial infarction (MI) treatment strategies remain challenged in suboptimal pharmacokinetics and potential adverse effects. Here we present a bioelectronic interface capable of producing on-demand abundant bioactive extracellular vesicles (EVs) near the MI area for in-situ local...

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Bibliographic Details
Main Authors: Siyuan Fu, Zhiyu Wang, Peihong Huang, Guanjun Li, Jian Niu, Zhiyang Li, Guangyue Zu, Pengcheng Zhou, Lianhui Wang, David Tai Leong, Xianguang Ding
Format: Article
Language:English
Published: Nature Portfolio 2025-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-58260-0
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