The quality of human eggs and its pre‐IVF incubation

Abstract Background Multi‐factors influence the success rate of infertility treatments, and one of the important points is to obtain good quality eggs. Methods Based on the literatures and unpublished data, the factors affecting egg quality were summarized. Main Findings (Results) Egg quality is an...

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Main Authors: Ri‐Cheng Chian, Yi‐Chun Guan, Xiao‐Jin He, Jian Xu, Jin‐Hui Shu, Jian‐Hua Li
Format: Article
Language:English
Published: Wiley 2025-01-01
Series:Reproductive Medicine and Biology
Subjects:
Online Access:https://doi.org/10.1002/rmb2.12652
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author Ri‐Cheng Chian
Yi‐Chun Guan
Xiao‐Jin He
Jian Xu
Jin‐Hui Shu
Jian‐Hua Li
author_facet Ri‐Cheng Chian
Yi‐Chun Guan
Xiao‐Jin He
Jian Xu
Jin‐Hui Shu
Jian‐Hua Li
author_sort Ri‐Cheng Chian
collection DOAJ
description Abstract Background Multi‐factors influence the success rate of infertility treatments, and one of the important points is to obtain good quality eggs. Methods Based on the literatures and unpublished data, the factors affecting egg quality were summarized. Main Findings (Results) Egg quality is an important determinant in successful infertility treatment. In addition to maternal age, controlled ovarian hyperstimulation (COH) protocols also play a key role in affecting the quality of the egg. After egg retrieval, the insemination occurs 3–6 h after collection, with a pre‐IVF incubation time by in vitro fertilization (IVF) or intracytoplasmic sperm injection (ICSI) (39–42 h post‐HCG injection). The pre‐IVF incubation refers to the short period time of 3 to 6 h after oocyte retrieval and before the insemination by IVF or ICSI. The pre‐IVF incubation of collected eggs in the designed culture medium improves egg quality in terms of maturation and early embryonic development. Conclusions Pre‐IVF incubation of the collected eggs contributes to the improvement of the quality of eggs; therefore, it may increase subsequent pregnancy and implantation rates following embryo transfer.
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institution Kabale University
issn 1445-5781
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publishDate 2025-01-01
publisher Wiley
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series Reproductive Medicine and Biology
spelling doaj-art-ff3ce501c55344f691753c010cc35ed42025-08-20T06:16:47ZengWileyReproductive Medicine and Biology1445-57811447-05782025-01-01241n/an/a10.1002/rmb2.12652The quality of human eggs and its pre‐IVF incubationRi‐Cheng Chian0Yi‐Chun Guan1Xiao‐Jin He2Jian Xu3Jin‐Hui Shu4Jian‐Hua Li5Laboratory of Research and Development ARSCI Biomedical Inc. Jiaxing City People's Republic of ChinaCenter for Reproductive Medicine The Third Affiliated Hospital of Zhengzhou University Zhengzhou City People's Republic of ChinaCenter for Reproductive Medicine The First People's Hospital of Jiaotong University Shanghai People's Republic of ChinaCenter for Reproductive Medicine The Fourth Affiliated Hospital, Zhejiang University School of Medicine Yiwu People's Republic of ChinaCenter of Reproductive Medicine Maternal and Child Health Hospital of Guangxi Zhuang Autonomous Region Nanning People's Republic of ChinaReproductive Medical Center, Department of Obstetrics and Gynecology Seventh Medical Center of PLA General Hospital Beijing People's Republic of ChinaAbstract Background Multi‐factors influence the success rate of infertility treatments, and one of the important points is to obtain good quality eggs. Methods Based on the literatures and unpublished data, the factors affecting egg quality were summarized. Main Findings (Results) Egg quality is an important determinant in successful infertility treatment. In addition to maternal age, controlled ovarian hyperstimulation (COH) protocols also play a key role in affecting the quality of the egg. After egg retrieval, the insemination occurs 3–6 h after collection, with a pre‐IVF incubation time by in vitro fertilization (IVF) or intracytoplasmic sperm injection (ICSI) (39–42 h post‐HCG injection). The pre‐IVF incubation refers to the short period time of 3 to 6 h after oocyte retrieval and before the insemination by IVF or ICSI. The pre‐IVF incubation of collected eggs in the designed culture medium improves egg quality in terms of maturation and early embryonic development. Conclusions Pre‐IVF incubation of the collected eggs contributes to the improvement of the quality of eggs; therefore, it may increase subsequent pregnancy and implantation rates following embryo transfer.https://doi.org/10.1002/rmb2.12652egghumanoocytepre‐IVF incubationquality
spellingShingle Ri‐Cheng Chian
Yi‐Chun Guan
Xiao‐Jin He
Jian Xu
Jin‐Hui Shu
Jian‐Hua Li
The quality of human eggs and its pre‐IVF incubation
Reproductive Medicine and Biology
egg
human
oocyte
pre‐IVF incubation
quality
title The quality of human eggs and its pre‐IVF incubation
title_full The quality of human eggs and its pre‐IVF incubation
title_fullStr The quality of human eggs and its pre‐IVF incubation
title_full_unstemmed The quality of human eggs and its pre‐IVF incubation
title_short The quality of human eggs and its pre‐IVF incubation
title_sort quality of human eggs and its pre ivf incubation
topic egg
human
oocyte
pre‐IVF incubation
quality
url https://doi.org/10.1002/rmb2.12652
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