Clinico-pathological specificities of gingival carcinoma among 32 patients with oral cancer: a cross sectional retrospective and observational study

Abstract Background The study aimed to examine the prevalence of gingival cancers compared to other oral mucosal sites, analyze patient profiles, and identify risk factors. Materials and Methods A retrospective monocentric study was conducted at the Department of Oral Medicine of Bretonneau Hospital...

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Main Authors: Yasmine Smail, Max Troizier-Cheyne, Claire Manon Lutz, Anne-Laure Ejeil
Format: Article
Language:English
Published: BMC 2024-10-01
Series:BMC Oral Health
Subjects:
Online Access:https://doi.org/10.1186/s12903-024-05078-9
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author Yasmine Smail
Max Troizier-Cheyne
Claire Manon Lutz
Anne-Laure Ejeil
author_facet Yasmine Smail
Max Troizier-Cheyne
Claire Manon Lutz
Anne-Laure Ejeil
author_sort Yasmine Smail
collection DOAJ
description Abstract Background The study aimed to examine the prevalence of gingival cancers compared to other oral mucosal sites, analyze patient profiles, and identify risk factors. Materials and Methods A retrospective monocentric study was conducted at the Department of Oral Medicine of Bretonneau Hospital in Paris, France. 32 patients diagnosed with oral mucosal cancer were included. Data extracted from electronic medical records encompassed patient demographics, cancer type, lesion location, and tobacco/alcohol use. Results 46.9% were diagnosed with gingival cancer. Patients with gingival cancer had a mean age of 74.2 years old, higher than the mean age of 63.9 years old for those with non-gingival cancer. Men accounted for 60% of cases in the gingival cancer group. Squamous cell carcinoma was the predominant cancer type observed in both gingival and non-gingival cancers. Notably, 26.7% of gingival cancer patients used both alcohol and tobacco, all of them male. Among non-gingival cancer patients, 23.5% used both substances, with both sexes represented. Conclusion This study provides insights into the higher prevalence of oral squamous cell carcinoma among men with risk factors and highlights characteristics of gingival squamous cell carcinoma. Effective management strategies should include comprehensive clinical assessments to ensure early detection and intervention for improved outcomes.
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spelling doaj-art-ff3c555cda78478f98e35d090dc02a9e2025-08-20T02:18:33ZengBMCBMC Oral Health1472-68312024-10-012411910.1186/s12903-024-05078-9Clinico-pathological specificities of gingival carcinoma among 32 patients with oral cancer: a cross sectional retrospective and observational studyYasmine Smail0Max Troizier-Cheyne1Claire Manon Lutz2Anne-Laure Ejeil3Innovative Dental Materials and Interfaces Research Unit, Paris Cité UniversityInnovative Dental Materials and Interfaces Research Unit, Paris Cité UniversityFaculty of Odontology, Department of Oral Surgery, Paris Cité UniversityFaculty of Odontology, Department of Oral Surgery, Paris Cité UniversityAbstract Background The study aimed to examine the prevalence of gingival cancers compared to other oral mucosal sites, analyze patient profiles, and identify risk factors. Materials and Methods A retrospective monocentric study was conducted at the Department of Oral Medicine of Bretonneau Hospital in Paris, France. 32 patients diagnosed with oral mucosal cancer were included. Data extracted from electronic medical records encompassed patient demographics, cancer type, lesion location, and tobacco/alcohol use. Results 46.9% were diagnosed with gingival cancer. Patients with gingival cancer had a mean age of 74.2 years old, higher than the mean age of 63.9 years old for those with non-gingival cancer. Men accounted for 60% of cases in the gingival cancer group. Squamous cell carcinoma was the predominant cancer type observed in both gingival and non-gingival cancers. Notably, 26.7% of gingival cancer patients used both alcohol and tobacco, all of them male. Among non-gingival cancer patients, 23.5% used both substances, with both sexes represented. Conclusion This study provides insights into the higher prevalence of oral squamous cell carcinoma among men with risk factors and highlights characteristics of gingival squamous cell carcinoma. Effective management strategies should include comprehensive clinical assessments to ensure early detection and intervention for improved outcomes.https://doi.org/10.1186/s12903-024-05078-9Anatomic locationGingival cancerOral cancerOral squamous cell carcinoma
spellingShingle Yasmine Smail
Max Troizier-Cheyne
Claire Manon Lutz
Anne-Laure Ejeil
Clinico-pathological specificities of gingival carcinoma among 32 patients with oral cancer: a cross sectional retrospective and observational study
BMC Oral Health
Anatomic location
Gingival cancer
Oral cancer
Oral squamous cell carcinoma
title Clinico-pathological specificities of gingival carcinoma among 32 patients with oral cancer: a cross sectional retrospective and observational study
title_full Clinico-pathological specificities of gingival carcinoma among 32 patients with oral cancer: a cross sectional retrospective and observational study
title_fullStr Clinico-pathological specificities of gingival carcinoma among 32 patients with oral cancer: a cross sectional retrospective and observational study
title_full_unstemmed Clinico-pathological specificities of gingival carcinoma among 32 patients with oral cancer: a cross sectional retrospective and observational study
title_short Clinico-pathological specificities of gingival carcinoma among 32 patients with oral cancer: a cross sectional retrospective and observational study
title_sort clinico pathological specificities of gingival carcinoma among 32 patients with oral cancer a cross sectional retrospective and observational study
topic Anatomic location
Gingival cancer
Oral cancer
Oral squamous cell carcinoma
url https://doi.org/10.1186/s12903-024-05078-9
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