Neonatal Hypernatremic Dehydration Associated with Lactation Failure

Hypernatremic dehydration secondary to lactation failure remains a potentially life-threatening condition in countries where advanced laboratory investigations are scarce. An 11-day term baby with excessive weight loss (33.6%), reduced urine output, fever, jaundice, doughy skin, opisthotonus posturi...

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Main Authors: Zemichael Ogbe, Amanuel Kidane Andegiorgish, Aradom Habteab Zeray, Lingxia Zeng
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:Case Reports in Critical Care
Online Access:http://dx.doi.org/10.1155/2020/8879945
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author Zemichael Ogbe
Amanuel Kidane Andegiorgish
Aradom Habteab Zeray
Lingxia Zeng
author_facet Zemichael Ogbe
Amanuel Kidane Andegiorgish
Aradom Habteab Zeray
Lingxia Zeng
author_sort Zemichael Ogbe
collection DOAJ
description Hypernatremic dehydration secondary to lactation failure remains a potentially life-threatening condition in countries where advanced laboratory investigations are scarce. An 11-day term baby with excessive weight loss (33.6%), reduced urine output, fever, jaundice, doughy skin, opisthotonus posturing, and tachycardia with poor perfusion was presented to our neonatal care. The baby was diagnosed with shock with hypernatremic dehydration. An initial bolus of 20 ml/kg of N/S was repeated 3 times (each over 20 minutes), i.e., a total of 204 ml was given over 1 hr, until the vital signs were normalized to PR-145, RR-45, T-37.2°C, SPO2-100%, and CRT < 3 seconds, and the baby began to void urine. Free water deficit and sodium excess was managed by gradual and slow correction over 72 hours to prevent cerebral oedema and neurologic sequelae. The baby required reconstituted solutions of 5% D/W + 1/2 N/S at a rate of 27 ml/hr for 72 hrs. Sepsis and hyperbilirubinemia were treated with antibiotics and phototherapy. Management of symptomatic hypernatremic dehydration must be considered in settings with inadequate laboratory facilities.
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spelling doaj-art-ff2f90b193e54474aab780e8b454a0832025-02-03T06:05:29ZengWileyCase Reports in Critical Care2090-64202090-64392020-01-01202010.1155/2020/88799458879945Neonatal Hypernatremic Dehydration Associated with Lactation FailureZemichael Ogbe0Amanuel Kidane Andegiorgish1Aradom Habteab Zeray2Lingxia Zeng3Department of Neonatology, Orotta School of Medicine and Health Sciences, Orotta National Referral Hospital, Asmara, EritreaDepartment of Epidemiology and Biostatistics, Asmara College of Health Sciences, School of Public Health, P.O. Box 8566, Asmara, EritreaDepartment of Neonatology, Orotta School of Medicine and Health Sciences, Orotta National Referral Hospital, Asmara, EritreaDepartment of Epidemiology and Biostatistics, School of Public Health, Health Science Center, Xi’an Jiaotong University, Shaanxi 710061, ChinaHypernatremic dehydration secondary to lactation failure remains a potentially life-threatening condition in countries where advanced laboratory investigations are scarce. An 11-day term baby with excessive weight loss (33.6%), reduced urine output, fever, jaundice, doughy skin, opisthotonus posturing, and tachycardia with poor perfusion was presented to our neonatal care. The baby was diagnosed with shock with hypernatremic dehydration. An initial bolus of 20 ml/kg of N/S was repeated 3 times (each over 20 minutes), i.e., a total of 204 ml was given over 1 hr, until the vital signs were normalized to PR-145, RR-45, T-37.2°C, SPO2-100%, and CRT < 3 seconds, and the baby began to void urine. Free water deficit and sodium excess was managed by gradual and slow correction over 72 hours to prevent cerebral oedema and neurologic sequelae. The baby required reconstituted solutions of 5% D/W + 1/2 N/S at a rate of 27 ml/hr for 72 hrs. Sepsis and hyperbilirubinemia were treated with antibiotics and phototherapy. Management of symptomatic hypernatremic dehydration must be considered in settings with inadequate laboratory facilities.http://dx.doi.org/10.1155/2020/8879945
spellingShingle Zemichael Ogbe
Amanuel Kidane Andegiorgish
Aradom Habteab Zeray
Lingxia Zeng
Neonatal Hypernatremic Dehydration Associated with Lactation Failure
Case Reports in Critical Care
title Neonatal Hypernatremic Dehydration Associated with Lactation Failure
title_full Neonatal Hypernatremic Dehydration Associated with Lactation Failure
title_fullStr Neonatal Hypernatremic Dehydration Associated with Lactation Failure
title_full_unstemmed Neonatal Hypernatremic Dehydration Associated with Lactation Failure
title_short Neonatal Hypernatremic Dehydration Associated with Lactation Failure
title_sort neonatal hypernatremic dehydration associated with lactation failure
url http://dx.doi.org/10.1155/2020/8879945
work_keys_str_mv AT zemichaelogbe neonatalhypernatremicdehydrationassociatedwithlactationfailure
AT amanuelkidaneandegiorgish neonatalhypernatremicdehydrationassociatedwithlactationfailure
AT aradomhabteabzeray neonatalhypernatremicdehydrationassociatedwithlactationfailure
AT lingxiazeng neonatalhypernatremicdehydrationassociatedwithlactationfailure