Neonatal Hypernatremic Dehydration Associated with Lactation Failure
Hypernatremic dehydration secondary to lactation failure remains a potentially life-threatening condition in countries where advanced laboratory investigations are scarce. An 11-day term baby with excessive weight loss (33.6%), reduced urine output, fever, jaundice, doughy skin, opisthotonus posturi...
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Language: | English |
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Wiley
2020-01-01
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Series: | Case Reports in Critical Care |
Online Access: | http://dx.doi.org/10.1155/2020/8879945 |
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author | Zemichael Ogbe Amanuel Kidane Andegiorgish Aradom Habteab Zeray Lingxia Zeng |
author_facet | Zemichael Ogbe Amanuel Kidane Andegiorgish Aradom Habteab Zeray Lingxia Zeng |
author_sort | Zemichael Ogbe |
collection | DOAJ |
description | Hypernatremic dehydration secondary to lactation failure remains a potentially life-threatening condition in countries where advanced laboratory investigations are scarce. An 11-day term baby with excessive weight loss (33.6%), reduced urine output, fever, jaundice, doughy skin, opisthotonus posturing, and tachycardia with poor perfusion was presented to our neonatal care. The baby was diagnosed with shock with hypernatremic dehydration. An initial bolus of 20 ml/kg of N/S was repeated 3 times (each over 20 minutes), i.e., a total of 204 ml was given over 1 hr, until the vital signs were normalized to PR-145, RR-45, T-37.2°C, SPO2-100%, and CRT < 3 seconds, and the baby began to void urine. Free water deficit and sodium excess was managed by gradual and slow correction over 72 hours to prevent cerebral oedema and neurologic sequelae. The baby required reconstituted solutions of 5% D/W + 1/2 N/S at a rate of 27 ml/hr for 72 hrs. Sepsis and hyperbilirubinemia were treated with antibiotics and phototherapy. Management of symptomatic hypernatremic dehydration must be considered in settings with inadequate laboratory facilities. |
format | Article |
id | doaj-art-ff2f90b193e54474aab780e8b454a083 |
institution | Kabale University |
issn | 2090-6420 2090-6439 |
language | English |
publishDate | 2020-01-01 |
publisher | Wiley |
record_format | Article |
series | Case Reports in Critical Care |
spelling | doaj-art-ff2f90b193e54474aab780e8b454a0832025-02-03T06:05:29ZengWileyCase Reports in Critical Care2090-64202090-64392020-01-01202010.1155/2020/88799458879945Neonatal Hypernatremic Dehydration Associated with Lactation FailureZemichael Ogbe0Amanuel Kidane Andegiorgish1Aradom Habteab Zeray2Lingxia Zeng3Department of Neonatology, Orotta School of Medicine and Health Sciences, Orotta National Referral Hospital, Asmara, EritreaDepartment of Epidemiology and Biostatistics, Asmara College of Health Sciences, School of Public Health, P.O. Box 8566, Asmara, EritreaDepartment of Neonatology, Orotta School of Medicine and Health Sciences, Orotta National Referral Hospital, Asmara, EritreaDepartment of Epidemiology and Biostatistics, School of Public Health, Health Science Center, Xi’an Jiaotong University, Shaanxi 710061, ChinaHypernatremic dehydration secondary to lactation failure remains a potentially life-threatening condition in countries where advanced laboratory investigations are scarce. An 11-day term baby with excessive weight loss (33.6%), reduced urine output, fever, jaundice, doughy skin, opisthotonus posturing, and tachycardia with poor perfusion was presented to our neonatal care. The baby was diagnosed with shock with hypernatremic dehydration. An initial bolus of 20 ml/kg of N/S was repeated 3 times (each over 20 minutes), i.e., a total of 204 ml was given over 1 hr, until the vital signs were normalized to PR-145, RR-45, T-37.2°C, SPO2-100%, and CRT < 3 seconds, and the baby began to void urine. Free water deficit and sodium excess was managed by gradual and slow correction over 72 hours to prevent cerebral oedema and neurologic sequelae. The baby required reconstituted solutions of 5% D/W + 1/2 N/S at a rate of 27 ml/hr for 72 hrs. Sepsis and hyperbilirubinemia were treated with antibiotics and phototherapy. Management of symptomatic hypernatremic dehydration must be considered in settings with inadequate laboratory facilities.http://dx.doi.org/10.1155/2020/8879945 |
spellingShingle | Zemichael Ogbe Amanuel Kidane Andegiorgish Aradom Habteab Zeray Lingxia Zeng Neonatal Hypernatremic Dehydration Associated with Lactation Failure Case Reports in Critical Care |
title | Neonatal Hypernatremic Dehydration Associated with Lactation Failure |
title_full | Neonatal Hypernatremic Dehydration Associated with Lactation Failure |
title_fullStr | Neonatal Hypernatremic Dehydration Associated with Lactation Failure |
title_full_unstemmed | Neonatal Hypernatremic Dehydration Associated with Lactation Failure |
title_short | Neonatal Hypernatremic Dehydration Associated with Lactation Failure |
title_sort | neonatal hypernatremic dehydration associated with lactation failure |
url | http://dx.doi.org/10.1155/2020/8879945 |
work_keys_str_mv | AT zemichaelogbe neonatalhypernatremicdehydrationassociatedwithlactationfailure AT amanuelkidaneandegiorgish neonatalhypernatremicdehydrationassociatedwithlactationfailure AT aradomhabteabzeray neonatalhypernatremicdehydrationassociatedwithlactationfailure AT lingxiazeng neonatalhypernatremicdehydrationassociatedwithlactationfailure |