Serum and urine eosinophil-derived neurotoxin (EDN) levels predict biologic response in severe asthma

Serum and urine eosinophil-derived neurotoxin (EDN) levels predict biologic response in severe asthma

Background: Eosinophils are crucial in allergic inflammation, and their correlation with asthma severity has made them a focal point in predicting treatment outcomes. Blood eosinophil count is a commonly utilized marker. However, its limitations have prompted alternative biomarker exploration, such...

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Main Authors: Yu Ri Kang, MD, Hyunkyoung Kim, MS, MPH, Chae Eun Lee, BS, Jae-Woo Jung, MD, PhD, Ji-Yong Moon, MD, PhD, So Young Park, MD, MS, Sae-Hoon Kim, MD, PhD, Min-Suk Yang, MD, PhD, Byung Keun Kim, MD, PhD, Jae-Woo Kwon, MD, PhD, Hye-Kyung Park, MD, PhD, Young-Hee Nam, MD, PhD, Young-Joo Cho, MD, PhD, Taehoon Lee, MD, PhD, Ian M. Adcock, MD, PhD, Pank Bhavsar, MD, PhD, Kian Fan Chung, MD, PhD, Tae-Bum Kim, MD, PhD
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:World Allergy Organization Journal
Subjects:
Eosinophils
Allergic inflammation
Asthma
Eosinophil-derived neurotoxin
Blood eosinophil counts
Biologic therapies
Online Access:http://www.sciencedirect.com/science/article/pii/S1939455124001224
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