Management of desmoid-type fibromatosis involving peripheral nerves

Desmoid-type fibromatosis is an uncommon and aggressive neoplasia, associated with a high rate of recurrence. It is characterized by an infiltrative but benign fibroblastic proliferation occurring within the deep soft tissues. There is no consensus about the treatment of those tumors. We present a s...

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Main Authors: Mario G. Siqueira, Paulo L. Tavares, Roberto S. Martins, Carlos O. Heise, Luciano H.L. Foroni, Marcelo Bordalo, Roberto Falzoni
Format: Article
Language:English
Published: Thieme Revinter Publicações 2012-07-01
Series:Arquivos de Neuro-Psiquiatria
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Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2012000700008&lng=en&tlng=en
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author Mario G. Siqueira
Paulo L. Tavares
Roberto S. Martins
Carlos O. Heise
Luciano H.L. Foroni
Marcelo Bordalo
Roberto Falzoni
author_facet Mario G. Siqueira
Paulo L. Tavares
Roberto S. Martins
Carlos O. Heise
Luciano H.L. Foroni
Marcelo Bordalo
Roberto Falzoni
author_sort Mario G. Siqueira
collection DOAJ
description Desmoid-type fibromatosis is an uncommon and aggressive neoplasia, associated with a high rate of recurrence. It is characterized by an infiltrative but benign fibroblastic proliferation occurring within the deep soft tissues. There is no consensus about the treatment of those tumors. We present a surgical series of four cases, involving the brachial plexus (two cases), the median nerve and the medial brachial cutaneous nerve. Except for the last case, they were submitted to multiple surgical procedures and showed repeated recurrences. The diagnosis, the different ways of treatment and the prognosis of these tumoral lesions are discussed. Our results support the indication of radical surgery followed by radiotherapy as probably one of the best ways to treat those controversial lesions.
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institution OA Journals
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publishDate 2012-07-01
publisher Thieme Revinter Publicações
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series Arquivos de Neuro-Psiquiatria
spelling doaj-art-ff20ea48a89a49dab1c0a6a1d21b1f762025-08-20T02:22:44ZengThieme Revinter PublicaçõesArquivos de Neuro-Psiquiatria1678-42272012-07-0170751451910.1590/S0004-282X2012000700008S0004-282X2012000700008Management of desmoid-type fibromatosis involving peripheral nervesMario G. Siqueira0Paulo L. Tavares1Roberto S. Martins2Carlos O. Heise3Luciano H.L. Foroni4Marcelo Bordalo5Roberto Falzoni6Universidade de São PauloUniversidade de São PauloUniversidade de São PauloUniversidade de São PauloUniversidade de São PauloUniversidade de São PauloUniversidade de São PauloDesmoid-type fibromatosis is an uncommon and aggressive neoplasia, associated with a high rate of recurrence. It is characterized by an infiltrative but benign fibroblastic proliferation occurring within the deep soft tissues. There is no consensus about the treatment of those tumors. We present a surgical series of four cases, involving the brachial plexus (two cases), the median nerve and the medial brachial cutaneous nerve. Except for the last case, they were submitted to multiple surgical procedures and showed repeated recurrences. The diagnosis, the different ways of treatment and the prognosis of these tumoral lesions are discussed. Our results support the indication of radical surgery followed by radiotherapy as probably one of the best ways to treat those controversial lesions.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2012000700008&lng=en&tlng=enfibromatose tipo desmoidetumor desmoidefibromanervos periféricos
spellingShingle Mario G. Siqueira
Paulo L. Tavares
Roberto S. Martins
Carlos O. Heise
Luciano H.L. Foroni
Marcelo Bordalo
Roberto Falzoni
Management of desmoid-type fibromatosis involving peripheral nerves
Arquivos de Neuro-Psiquiatria
fibromatose tipo desmoide
tumor desmoide
fibroma
nervos periféricos
title Management of desmoid-type fibromatosis involving peripheral nerves
title_full Management of desmoid-type fibromatosis involving peripheral nerves
title_fullStr Management of desmoid-type fibromatosis involving peripheral nerves
title_full_unstemmed Management of desmoid-type fibromatosis involving peripheral nerves
title_short Management of desmoid-type fibromatosis involving peripheral nerves
title_sort management of desmoid type fibromatosis involving peripheral nerves
topic fibromatose tipo desmoide
tumor desmoide
fibroma
nervos periféricos
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2012000700008&lng=en&tlng=en
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AT carlosoheise managementofdesmoidtypefibromatosisinvolvingperipheralnerves
AT lucianohlforoni managementofdesmoidtypefibromatosisinvolvingperipheralnerves
AT marcelobordalo managementofdesmoidtypefibromatosisinvolvingperipheralnerves
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