Hormonal Changes in Menopause and Orexin-A Action
Menopause is a period of significant physiological changes that may be associated with increased body weight and obesity-related diseases. Many researches were conducted to assess the contribution of factors such as estrogen depletion, REE decline, and aging to weight gain. An increase in orexin-A p...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2013-01-01
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| Series: | Obstetrics and Gynecology International |
| Online Access: | http://dx.doi.org/10.1155/2013/209812 |
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| author | Giovanni Messina Andrea Viggiano Vincenzo De Luca Antonietta Messina Sergio Chieffi Marcellino Monda |
| author_facet | Giovanni Messina Andrea Viggiano Vincenzo De Luca Antonietta Messina Sergio Chieffi Marcellino Monda |
| author_sort | Giovanni Messina |
| collection | DOAJ |
| description | Menopause is a period of significant physiological changes that may be associated with increased body weight and obesity-related diseases. Many researches were conducted to assess the contribution of factors such as estrogen depletion, REE decline, and aging to weight gain. An increase in orexin-A plasma levels, paralleling lower estrogen levels, was found during menopause. Orexins are hypothalamic neuropeptides recently discovered, involved in the regulation of feeding behaviour, sleep-wakefulness rhythm, and neuroendocrine homeostasis. Orexins might offer the missing link between postmenopausal hypoestrogenism and other manifestations of the menopausal syndrome, including appetite and weight changes and increase in cardiovascular risk. |
| format | Article |
| id | doaj-art-ff1e2adec080428cb780519ed2a8eaff |
| institution | Kabale University |
| issn | 1687-9589 1687-9597 |
| language | English |
| publishDate | 2013-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Obstetrics and Gynecology International |
| spelling | doaj-art-ff1e2adec080428cb780519ed2a8eaff2025-02-03T06:07:20ZengWileyObstetrics and Gynecology International1687-95891687-95972013-01-01201310.1155/2013/209812209812Hormonal Changes in Menopause and Orexin-A ActionGiovanni Messina0Andrea Viggiano1Vincenzo De Luca2Antonietta Messina3Sergio Chieffi4Marcellino Monda5Department of Experimental Medicine, Section of Human Physiology and Clinical Dietetic Service, Second University of Naples, Via Costantinopoli 16, I-80138 Naples, ItalyFaculty of Medicine, University of Salerno, Salerno, ItalyDepartment of Experimental Medicine, Section of Human Physiology and Clinical Dietetic Service, Second University of Naples, Via Costantinopoli 16, I-80138 Naples, ItalyDepartment of Experimental Medicine, Section of Human Physiology and Clinical Dietetic Service, Second University of Naples, Via Costantinopoli 16, I-80138 Naples, ItalyDepartment of Experimental Medicine, Section of Human Physiology and Clinical Dietetic Service, Second University of Naples, Via Costantinopoli 16, I-80138 Naples, ItalyDepartment of Experimental Medicine, Section of Human Physiology and Clinical Dietetic Service, Second University of Naples, Via Costantinopoli 16, I-80138 Naples, ItalyMenopause is a period of significant physiological changes that may be associated with increased body weight and obesity-related diseases. Many researches were conducted to assess the contribution of factors such as estrogen depletion, REE decline, and aging to weight gain. An increase in orexin-A plasma levels, paralleling lower estrogen levels, was found during menopause. Orexins are hypothalamic neuropeptides recently discovered, involved in the regulation of feeding behaviour, sleep-wakefulness rhythm, and neuroendocrine homeostasis. Orexins might offer the missing link between postmenopausal hypoestrogenism and other manifestations of the menopausal syndrome, including appetite and weight changes and increase in cardiovascular risk.http://dx.doi.org/10.1155/2013/209812 |
| spellingShingle | Giovanni Messina Andrea Viggiano Vincenzo De Luca Antonietta Messina Sergio Chieffi Marcellino Monda Hormonal Changes in Menopause and Orexin-A Action Obstetrics and Gynecology International |
| title | Hormonal Changes in Menopause and Orexin-A Action |
| title_full | Hormonal Changes in Menopause and Orexin-A Action |
| title_fullStr | Hormonal Changes in Menopause and Orexin-A Action |
| title_full_unstemmed | Hormonal Changes in Menopause and Orexin-A Action |
| title_short | Hormonal Changes in Menopause and Orexin-A Action |
| title_sort | hormonal changes in menopause and orexin a action |
| url | http://dx.doi.org/10.1155/2013/209812 |
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