Synthesis of Fluorine Heterocyclic Nitrogen Systems Derived From Sulfa Drugs as PhotochemicalProbe Agents for Inhibition of Vitiligo Disease-Part II
Some more new bioactive fluorine heterocyclic systems containing sulfur and nitrogen as six-membered rings such as; N,Nʼ-disubstituted-thiobarbituric acid, 3-thioxo-1,2,4-triazino[5,6-b]indole, 3-sulfanilamido-1,2,4-triazino[5,6-b]indole and 2-trifluoromethyl-4-imino-6-(sulfamido)1,3,5-triazino [3,2...
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| Format: | Article |
| Language: | English |
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Wiley
2010-01-01
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| Series: | E-Journal of Chemistry |
| Online Access: | http://dx.doi.org/10.1155/2010/467564 |
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| author | Reda M. Abdel-Rahman Mohammad Saleh I. T. Makki Wafa A. Baker Bawazir |
| author_facet | Reda M. Abdel-Rahman Mohammad Saleh I. T. Makki Wafa A. Baker Bawazir |
| author_sort | Reda M. Abdel-Rahman |
| collection | DOAJ |
| description | Some more new bioactive fluorine heterocyclic systems containing sulfur and nitrogen as six-membered rings such as; N,Nʼ-disubstituted-thiobarbituric acid, 3-thioxo-1,2,4-triazino[5,6-b]indole, 3-sulfanilamido-1,2,4-triazino[5,6-b]indole and 2-trifluoromethyl-4-imino-6-(sulfamido)1,3,5-triazino [3,2-a]indole derivatives (2-13) have been synthetically derived from the interaction of sulfa drugs with fluorine organic compounds (aldehydes, ketones, anhydride) followed by ring closure reactions. Structures of the targets have been established from their elemental and spectral data. Compounds 3, 6, 10 and 13 could be used as photochemical probe agents in compared with nystatin and nalidixic acid for inhibition of vitiligo diseases. |
| format | Article |
| id | doaj-art-ff1693c0c07f46a4a3a53fb43fa22c02 |
| institution | Kabale University |
| issn | 0973-4945 2090-9810 |
| language | English |
| publishDate | 2010-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | E-Journal of Chemistry |
| spelling | doaj-art-ff1693c0c07f46a4a3a53fb43fa22c022025-02-03T01:23:29ZengWileyE-Journal of Chemistry0973-49452090-98102010-01-017S1S93S10210.1155/2010/467564Synthesis of Fluorine Heterocyclic Nitrogen Systems Derived From Sulfa Drugs as PhotochemicalProbe Agents for Inhibition of Vitiligo Disease-Part IIReda M. Abdel-Rahman0Mohammad Saleh I. T. Makki1Wafa A. Baker Bawazir2Department of Chemistry, Faculty of Science, King Abdul-Aziz University, P.O.Box 80203, Jeddah 21315, Saudi ArabiaDepartment of Chemistry, Faculty of Science, King Abdul-Aziz University, P.O.Box 80203, Jeddah 21315, Saudi ArabiaDepartment of Chemistry, Faculty of Science, King Abdul-Aziz University, P.O.Box 80203, Jeddah 21315, Saudi ArabiaSome more new bioactive fluorine heterocyclic systems containing sulfur and nitrogen as six-membered rings such as; N,Nʼ-disubstituted-thiobarbituric acid, 3-thioxo-1,2,4-triazino[5,6-b]indole, 3-sulfanilamido-1,2,4-triazino[5,6-b]indole and 2-trifluoromethyl-4-imino-6-(sulfamido)1,3,5-triazino [3,2-a]indole derivatives (2-13) have been synthetically derived from the interaction of sulfa drugs with fluorine organic compounds (aldehydes, ketones, anhydride) followed by ring closure reactions. Structures of the targets have been established from their elemental and spectral data. Compounds 3, 6, 10 and 13 could be used as photochemical probe agents in compared with nystatin and nalidixic acid for inhibition of vitiligo diseases.http://dx.doi.org/10.1155/2010/467564 |
| spellingShingle | Reda M. Abdel-Rahman Mohammad Saleh I. T. Makki Wafa A. Baker Bawazir Synthesis of Fluorine Heterocyclic Nitrogen Systems Derived From Sulfa Drugs as PhotochemicalProbe Agents for Inhibition of Vitiligo Disease-Part II E-Journal of Chemistry |
| title | Synthesis of Fluorine Heterocyclic Nitrogen Systems Derived From Sulfa Drugs as PhotochemicalProbe Agents for Inhibition of Vitiligo Disease-Part II |
| title_full | Synthesis of Fluorine Heterocyclic Nitrogen Systems Derived From Sulfa Drugs as PhotochemicalProbe Agents for Inhibition of Vitiligo Disease-Part II |
| title_fullStr | Synthesis of Fluorine Heterocyclic Nitrogen Systems Derived From Sulfa Drugs as PhotochemicalProbe Agents for Inhibition of Vitiligo Disease-Part II |
| title_full_unstemmed | Synthesis of Fluorine Heterocyclic Nitrogen Systems Derived From Sulfa Drugs as PhotochemicalProbe Agents for Inhibition of Vitiligo Disease-Part II |
| title_short | Synthesis of Fluorine Heterocyclic Nitrogen Systems Derived From Sulfa Drugs as PhotochemicalProbe Agents for Inhibition of Vitiligo Disease-Part II |
| title_sort | synthesis of fluorine heterocyclic nitrogen systems derived from sulfa drugs as photochemicalprobe agents for inhibition of vitiligo disease part ii |
| url | http://dx.doi.org/10.1155/2010/467564 |
| work_keys_str_mv | AT redamabdelrahman synthesisoffluorineheterocyclicnitrogensystemsderivedfromsulfadrugsasphotochemicalprobeagentsforinhibitionofvitiligodiseasepartii AT mohammadsalehitmakki synthesisoffluorineheterocyclicnitrogensystemsderivedfromsulfadrugsasphotochemicalprobeagentsforinhibitionofvitiligodiseasepartii AT wafaabakerbawazir synthesisoffluorineheterocyclicnitrogensystemsderivedfromsulfadrugsasphotochemicalprobeagentsforinhibitionofvitiligodiseasepartii |