Long-term endocrine outcomes and quality of life in paediatric and young chronic myeloid leukaemia patients on tyrosine kinase inhibitor therapy: a prospective study from India

Long-term endocrine outcomes and quality of life in paediatric and young chronic myeloid leukaemia patients on tyrosine kinase inhibitor therapy: a prospective study from India

BackgroundChronic myeloid leukaemia (CML) is rare in paediatric population, approximately 2–3% of leukaemia cases in children and 9% in adolescents. The introduction of tyrosine kinase inhibitors (TKIs) has significantly improved outcomes, but long-term use may lead to adverse endocrine effects and...

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Bibliographic Details
Main Authors: Rajiv Mohan, Chitrakshi Nagpal, Swasthik Upadhya, Akash Kumar, Rajesh Khadgawat, Sameer Bakhshi, Deepam Pushpam
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Oncology
Subjects:
endocrine effects
quality of life
CML
paediatric
young
TKI
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2025.1598104/full
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