The antifibrillatory activity study of the compound LMG-124 and lappaconitine hydrobromide on the reperfusion arrhythmias model

The antifibrillatory activity comparative study of the compound LMG-124 and the reference drug Lappaconitine hydrobromide was performed on the model of reperfusion arrhythmias. Both drugs are shown to exhibit antiarrhythmic and antifibrillatory activity, but the compound LMG-124 realizes its effect...

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Main Authors: V. N. Stolyaruk, I. B. Tsorin, M. B. Vititnova, V. P. Gusev, Yu. I. Murinov, M. S. Yunusov, S. A. Kryzhanovskii
Format: Article
Language:Russian
Published: LLC “Publisher OKI” 2017-03-01
Series:Фармакокинетика и Фармакодинамика
Subjects:
Online Access:https://www.pharmacokinetica.ru/jour/article/view/13
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author V. N. Stolyaruk
I. B. Tsorin
M. B. Vititnova
V. P. Gusev
Yu. I. Murinov
M. S. Yunusov
S. A. Kryzhanovskii
author_facet V. N. Stolyaruk
I. B. Tsorin
M. B. Vititnova
V. P. Gusev
Yu. I. Murinov
M. S. Yunusov
S. A. Kryzhanovskii
author_sort V. N. Stolyaruk
collection DOAJ
description The antifibrillatory activity comparative study of the compound LMG-124 and the reference drug Lappaconitine hydrobromide was performed on the model of reperfusion arrhythmias. Both drugs are shown to exhibit antiarrhythmic and antifibrillatory activity, but the compound LMG-124 realizes its effect in a significantly lower dose.
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institution DOAJ
issn 2587-7836
2686-8830
language Russian
publishDate 2017-03-01
publisher LLC “Publisher OKI”
record_format Article
series Фармакокинетика и Фармакодинамика
spelling doaj-art-ff0a04642dc74a799ea1d8c8ea759c2d2025-08-20T02:49:52ZrusLLC “Publisher OKI”Фармакокинетика и Фармакодинамика2587-78362686-88302017-03-0102161812The antifibrillatory activity study of the compound LMG-124 and lappaconitine hydrobromide on the reperfusion arrhythmias modelV. N. Stolyaruk0I. B. Tsorin1M. B. Vititnova2V. P. Gusev3Yu. I. Murinov4M. S. Yunusov5S. A. Kryzhanovskii6FSBI «Zakusov Institute of Pharmacology»FSBI «Zakusov Institute of Pharmacology»FSBI «Zakusov Institute of Pharmacology»FSBI «Zakusov Institute of Pharmacology»FSBIS «Ufa Institute of Chemistry of the Russian Academy of Sciences» (UIC RAS)FSBIS «Ufa Institute of Chemistry of the Russian Academy of Sciences» (UIC RAS)FSBI «Zakusov Institute of Pharmacology»The antifibrillatory activity comparative study of the compound LMG-124 and the reference drug Lappaconitine hydrobromide was performed on the model of reperfusion arrhythmias. Both drugs are shown to exhibit antiarrhythmic and antifibrillatory activity, but the compound LMG-124 realizes its effect in a significantly lower dose.https://www.pharmacokinetica.ru/jour/article/view/13лаппаконитина гидробромидлмг-124реперфузионные аритмииlappaconitine hydrobromidelmg-124reperfusion arrhythmias
spellingShingle V. N. Stolyaruk
I. B. Tsorin
M. B. Vititnova
V. P. Gusev
Yu. I. Murinov
M. S. Yunusov
S. A. Kryzhanovskii
The antifibrillatory activity study of the compound LMG-124 and lappaconitine hydrobromide on the reperfusion arrhythmias model
Фармакокинетика и Фармакодинамика
лаппаконитина гидробромид
лмг-124
реперфузионные аритмии
lappaconitine hydrobromide
lmg-124
reperfusion arrhythmias
title The antifibrillatory activity study of the compound LMG-124 and lappaconitine hydrobromide on the reperfusion arrhythmias model
title_full The antifibrillatory activity study of the compound LMG-124 and lappaconitine hydrobromide on the reperfusion arrhythmias model
title_fullStr The antifibrillatory activity study of the compound LMG-124 and lappaconitine hydrobromide on the reperfusion arrhythmias model
title_full_unstemmed The antifibrillatory activity study of the compound LMG-124 and lappaconitine hydrobromide on the reperfusion arrhythmias model
title_short The antifibrillatory activity study of the compound LMG-124 and lappaconitine hydrobromide on the reperfusion arrhythmias model
title_sort antifibrillatory activity study of the compound lmg 124 and lappaconitine hydrobromide on the reperfusion arrhythmias model
topic лаппаконитина гидробромид
лмг-124
реперфузионные аритмии
lappaconitine hydrobromide
lmg-124
reperfusion arrhythmias
url https://www.pharmacokinetica.ru/jour/article/view/13
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