An investigation of the Effect of Antihypertensive drugs on Arteriovenous Fistula Maturation in Patients with Hemodialysis
Background: The maturation of the arteriovenous fistula (AVF) is necessary for successful hemodialysis treatment. However, the role of antihypertensive drugs in influencing AVF maturation remains uncertain. This study investigated the AVF maturation in patients with renal failure treated with antihy...
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Babol University of Medical Sciences
2025-06-01
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| Series: | Caspian Journal of Internal Medicine |
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| Online Access: | http://caspjim.com/article-1-4213-en.pdf |
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| author | Fatemeh Mahmoudlou Pouya Tayebi Aliakbar Moghadamnia Ali Bijani |
| author_facet | Fatemeh Mahmoudlou Pouya Tayebi Aliakbar Moghadamnia Ali Bijani |
| author_sort | Fatemeh Mahmoudlou |
| collection | DOAJ |
| description | Background: The maturation of the arteriovenous fistula (AVF) is necessary for successful hemodialysis treatment. However, the role of antihypertensive drugs in influencing AVF maturation remains uncertain. This study investigated the AVF maturation in patients with renal failure treated with antihypertensive medications.
Methods: A prospective cohort study was conducted on 73 patients who needed to be treated with hemodialysis through AVF. Demographic information, medication, underlying diseases, blood pressure changes, surgical information, and the time of AVF maturation were collected during the study. Descriptive statistics and survival analysis were employed to assess the outcomes.
Results: The mean age of patients was 53.96±13.65 years, with 38 (52.1%) males and 35 (47.9%) females. The mean AVF maturation time was 104.87±1.02 days, and the rate of AVF maturation was 87.7%. Among the comorbidities, the rate of AVF maturation in diabetic patients (78.4%) versus non-diabetic (97.2%) exhibited a notably diminished effect (P = 0.028). There was a significant association between mean intraoperative arterial blood pressure (123.45±2.89 mmHg) and AVF maturation time (P = 0.033). Furthermore, there were not any significant differences in the use of antihypertensive medications on AVF maturation time or rates.
Conclusion: Our study findings suggest that the administration of antihypertensive medications did not demonstrate a significant correlation with either the AVF maturation outcome or the time required for maturation. |
| format | Article |
| id | doaj-art-feff70d3c19949ef8944ccc16feca743 |
| institution | OA Journals |
| issn | 2008-6164 2008-6172 |
| language | English |
| publishDate | 2025-06-01 |
| publisher | Babol University of Medical Sciences |
| record_format | Article |
| series | Caspian Journal of Internal Medicine |
| spelling | doaj-art-feff70d3c19949ef8944ccc16feca7432025-08-20T02:38:59ZengBabol University of Medical SciencesCaspian Journal of Internal Medicine2008-61642008-61722025-06-01163500506An investigation of the Effect of Antihypertensive drugs on Arteriovenous Fistula Maturation in Patients with HemodialysisFatemeh Mahmoudlou0Pouya Tayebi1Aliakbar Moghadamnia2Ali Bijani3 Student Research Committee, Babol University of Medical Sciences, Babol, Iran Department of Vascular and Endovascular Surgery, Rouhani Hospital, Babol University of Medical Sciences, Babol, Iran Department of Pharmacology and Toxicology, School of Medicine, Babol University of Medical Sciences, Babol, Iran Social Determinants of Health Research Center, Babol University of Medical Sciences, Babol, Iran Background: The maturation of the arteriovenous fistula (AVF) is necessary for successful hemodialysis treatment. However, the role of antihypertensive drugs in influencing AVF maturation remains uncertain. This study investigated the AVF maturation in patients with renal failure treated with antihypertensive medications. Methods: A prospective cohort study was conducted on 73 patients who needed to be treated with hemodialysis through AVF. Demographic information, medication, underlying diseases, blood pressure changes, surgical information, and the time of AVF maturation were collected during the study. Descriptive statistics and survival analysis were employed to assess the outcomes. Results: The mean age of patients was 53.96±13.65 years, with 38 (52.1%) males and 35 (47.9%) females. The mean AVF maturation time was 104.87±1.02 days, and the rate of AVF maturation was 87.7%. Among the comorbidities, the rate of AVF maturation in diabetic patients (78.4%) versus non-diabetic (97.2%) exhibited a notably diminished effect (P = 0.028). There was a significant association between mean intraoperative arterial blood pressure (123.45±2.89 mmHg) and AVF maturation time (P = 0.033). Furthermore, there were not any significant differences in the use of antihypertensive medications on AVF maturation time or rates. Conclusion: Our study findings suggest that the administration of antihypertensive medications did not demonstrate a significant correlation with either the AVF maturation outcome or the time required for maturation.http://caspjim.com/article-1-4213-en.pdfarteriovenous fistulaantihypertensive agentsrenal dialysisarteriovenous fistula maturationblood pressure |
| spellingShingle | Fatemeh Mahmoudlou Pouya Tayebi Aliakbar Moghadamnia Ali Bijani An investigation of the Effect of Antihypertensive drugs on Arteriovenous Fistula Maturation in Patients with Hemodialysis Caspian Journal of Internal Medicine arteriovenous fistula antihypertensive agents renal dialysis arteriovenous fistula maturation blood pressure |
| title | An investigation of the Effect of Antihypertensive drugs on Arteriovenous Fistula Maturation in Patients with Hemodialysis |
| title_full | An investigation of the Effect of Antihypertensive drugs on Arteriovenous Fistula Maturation in Patients with Hemodialysis |
| title_fullStr | An investigation of the Effect of Antihypertensive drugs on Arteriovenous Fistula Maturation in Patients with Hemodialysis |
| title_full_unstemmed | An investigation of the Effect of Antihypertensive drugs on Arteriovenous Fistula Maturation in Patients with Hemodialysis |
| title_short | An investigation of the Effect of Antihypertensive drugs on Arteriovenous Fistula Maturation in Patients with Hemodialysis |
| title_sort | investigation of the effect of antihypertensive drugs on arteriovenous fistula maturation in patients with hemodialysis |
| topic | arteriovenous fistula antihypertensive agents renal dialysis arteriovenous fistula maturation blood pressure |
| url | http://caspjim.com/article-1-4213-en.pdf |
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