Differential regulation of metalloproteinase production, proliferation and chemotaxis of human lung fibroblasts by PDGF, Interleukin-1β and TNF-α

Fibroblast migration, proliferation, extracellular matrix protein synthesis and degradation,all of which play important roles in inflammation, are them selves induced by various growth factors and cytokines. Less is known about the interaction of these substances on lung fibroblast function in pulmo...

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Main Authors: Masahiro Sasaki, Masayuki Kashima, Takefumi Ito, Akiko Watanabe, Noriko Izumiyama, Masaaki Sano, Manabu Kagaya, Takanobu Shioya, Mamoru Miura
Format: Article
Language:English
Published: Wiley 2000-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1080/09629350020002895
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author Masahiro Sasaki
Masayuki Kashima
Takefumi Ito
Akiko Watanabe
Noriko Izumiyama
Masaaki Sano
Manabu Kagaya
Takanobu Shioya
Mamoru Miura
author_facet Masahiro Sasaki
Masayuki Kashima
Takefumi Ito
Akiko Watanabe
Noriko Izumiyama
Masaaki Sano
Manabu Kagaya
Takanobu Shioya
Mamoru Miura
author_sort Masahiro Sasaki
collection DOAJ
description Fibroblast migration, proliferation, extracellular matrix protein synthesis and degradation,all of which play important roles in inflammation, are them selves induced by various growth factors and cytokines. Less is known about the interaction of these substances on lung fibroblast function in pulmonary fibrosis.
format Article
id doaj-art-fefdb1b85e684734ae68a45243603b9b
institution Kabale University
issn 0962-9351
1466-1861
language English
publishDate 2000-01-01
publisher Wiley
record_format Article
series Mediators of Inflammation
spelling doaj-art-fefdb1b85e684734ae68a45243603b9b2025-02-03T01:22:32ZengWileyMediators of Inflammation0962-93511466-18612000-01-0193-415516010.1080/09629350020002895Differential regulation of metalloproteinase production, proliferation and chemotaxis of human lung fibroblasts by PDGF, Interleukin-1β and TNF-αMasahiro Sasaki0Masayuki Kashima1Takefumi Ito2Akiko Watanabe3Noriko Izumiyama4Masaaki Sano5Manabu Kagaya6Takanobu Shioya7Mamoru Miura8Second Department of Internal Medicine, Akita University School of Medicine, 1–1–1 Hondo, Akita 010, JapanSecond Department of Internal Medicine, Akita University School of Medicine, 1–1–1 Hondo, Akita 010, JapanSecond Department of Internal Medicine, Akita University School of Medicine, 1–1–1 Hondo, Akita 010, JapanSecond Department of Internal Medicine, Akita University School of Medicine, 1–1–1 Hondo, Akita 010, JapanSecond Department of Internal Medicine, Akita University School of Medicine, 1–1–1 Hondo, Akita 010, JapanSecond Department of Internal Medicine, Akita University School of Medicine, 1–1–1 Hondo, Akita 010, JapanSecond Department of Internal Medicine, Akita University School of Medicine, 1–1–1 Hondo, Akita 010, JapanSecond Department of Internal Medicine, Akita University School of Medicine, 1–1–1 Hondo, Akita 010, JapanSecond Department of Internal Medicine, Akita University School of Medicine, 1–1–1 Hondo, Akita 010, JapanFibroblast migration, proliferation, extracellular matrix protein synthesis and degradation,all of which play important roles in inflammation, are them selves induced by various growth factors and cytokines. Less is known about the interaction of these substances on lung fibroblast function in pulmonary fibrosis.http://dx.doi.org/10.1080/09629350020002895
spellingShingle Masahiro Sasaki
Masayuki Kashima
Takefumi Ito
Akiko Watanabe
Noriko Izumiyama
Masaaki Sano
Manabu Kagaya
Takanobu Shioya
Mamoru Miura
Differential regulation of metalloproteinase production, proliferation and chemotaxis of human lung fibroblasts by PDGF, Interleukin-1β and TNF-α
Mediators of Inflammation
title Differential regulation of metalloproteinase production, proliferation and chemotaxis of human lung fibroblasts by PDGF, Interleukin-1β and TNF-α
title_full Differential regulation of metalloproteinase production, proliferation and chemotaxis of human lung fibroblasts by PDGF, Interleukin-1β and TNF-α
title_fullStr Differential regulation of metalloproteinase production, proliferation and chemotaxis of human lung fibroblasts by PDGF, Interleukin-1β and TNF-α
title_full_unstemmed Differential regulation of metalloproteinase production, proliferation and chemotaxis of human lung fibroblasts by PDGF, Interleukin-1β and TNF-α
title_short Differential regulation of metalloproteinase production, proliferation and chemotaxis of human lung fibroblasts by PDGF, Interleukin-1β and TNF-α
title_sort differential regulation of metalloproteinase production proliferation and chemotaxis of human lung fibroblasts by pdgf interleukin 1β and tnf α
url http://dx.doi.org/10.1080/09629350020002895
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