Assessing fatigue and related factors in adolescents with familial Mediterranean fever (FMF): psychometric properties of the PedsQL Multidimensional Fatigue Scale

Background. Fatigue is a common problem in pediatric rheumatic diseases and is associated with poor quality of life. However, no validated methods are available to measure fatigue in adolescents with familial Mediterranean fever (FMF). The aim of the study was to establish validity and reliab...

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Main Authors: Devrim Can Saraç, Ece Pastutmaz, Sena Kongur, Cennet Hanım Karakurt, İdil Akar, İsrafil İnanç, Özge Altuğ Gücenmez, Belde Kasap Demir, Serkan Metin, Deniz Bayraktar
Format: Article
Language:English
Published: Hacettepe University Institute of Child Health 2023-08-01
Series:The Turkish Journal of Pediatrics
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Online Access:https://turkjpediatr.org/article/view/70
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author Devrim Can Saraç
Ece Pastutmaz
Sena Kongur
Cennet Hanım Karakurt
İdil Akar
İsrafil İnanç
Özge Altuğ Gücenmez
Belde Kasap Demir
Serkan Metin
Deniz Bayraktar
author_facet Devrim Can Saraç
Ece Pastutmaz
Sena Kongur
Cennet Hanım Karakurt
İdil Akar
İsrafil İnanç
Özge Altuğ Gücenmez
Belde Kasap Demir
Serkan Metin
Deniz Bayraktar
author_sort Devrim Can Saraç
collection DOAJ
description Background. Fatigue is a common problem in pediatric rheumatic diseases and is associated with poor quality of life. However, no validated methods are available to measure fatigue in adolescents with familial Mediterranean fever (FMF). The aim of the study was to establish validity and reliability for the child self-report PedsQL Multidimensional Fatigue Scale (PedsQL-MFS) and to investigate the effects of physical characteristics, diseaserelated characteristics, sleep quality/duration, and the amount of physical activity on fatigue in adolescents with FMF. Methods. Seventy-one adolescents with FMF (13-18 years) were included. Children were examined regarding physical- and disease-related characteristics and completed patient-reported outcome measures (PROMs) regarding sleep quality/duration, physical activity levels, and fatigue. PedsQL-MFS was re-completed within the following 7-14 days. Results. PedsQL-MFS demonstrated excellent test-retest reliability (ICC in 95% CI: 0.877-0.958) and internal consistency (Cronbach`s α: 0.928). All items contributed to the total score (item-total correlation > 0.3). PedsQLMFS scores were significantly correlated to fatigue (r: -0.666, p < 0.001), physical activity (r: 0.373, p < 0.001), sleep quality (rs: 0.678, p < 0.001), and sleep duration (r: 0.473, p < 0.001). Being female, having attacks in the last six months, a sleep duration of less than seven hours, and engaging in less physical activity resulted in higher fatigue. Conclusions. PedsQL-MFS seems to be feasible for assessing fatigue in adolescents with FMF. Sex, recent attacks, sleep, and physical activity should be taken into consideration in the fatigue management of patients with FMF.
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publishDate 2023-08-01
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spelling doaj-art-fefcb17243c84d3f82ee677d2b7cbf922025-08-20T02:55:38ZengHacettepe University Institute of Child HealthThe Turkish Journal of Pediatrics0041-43012791-64212023-08-0165410.24953/turkjped.2023.122Assessing fatigue and related factors in adolescents with familial Mediterranean fever (FMF): psychometric properties of the PedsQL Multidimensional Fatigue ScaleDevrim Can Saraç0Ece Pastutmaz1Sena Kongur2Cennet Hanım Karakurt3İdil Akar4İsrafil İnanç5Özge Altuğ Gücenmez6Belde Kasap Demir7Serkan Metin8Deniz Bayraktar9Department of Physiotherapy and Rehabilitation, Faculty of Health Sciences, İzmir Katip Çelebi University, İzmir.Department of Physiotherapy and Rehabilitation, Faculty of Health Sciences, İzmir Katip Çelebi University, İzmir.Department of Physiotherapy and Rehabilitation, Faculty of Health Sciences, İzmir Katip Çelebi University, İzmir.Department of Physiotherapy and Rehabilitation, Faculty of Health Sciences, İzmir Katip Çelebi University, İzmir.Department of Physiotherapy and Rehabilitation, Faculty of Health Sciences, İzmir Katip Çelebi University, İzmir.Institute of Health Sciences, İzmir Katip Çelebi University, İzmir, Türkiye.Clinic of Pediatric Rheumatology, Dr. Behcet Uz Pediatric Diseases and Surgery Training and Research Hospital, İzmir.Department of Pediatrics, Faculty of Medicine, İzmir Katip Çelebi University, İzmir.Department of Physiotherapy and Rehabilitation, Faculty of Health Sciences, İzmir Katip Çelebi University, İzmir.Department of Physiotherapy and Rehabilitation, Faculty of Health Sciences, İzmir Katip Çelebi University, İzmir. Background. Fatigue is a common problem in pediatric rheumatic diseases and is associated with poor quality of life. However, no validated methods are available to measure fatigue in adolescents with familial Mediterranean fever (FMF). The aim of the study was to establish validity and reliability for the child self-report PedsQL Multidimensional Fatigue Scale (PedsQL-MFS) and to investigate the effects of physical characteristics, diseaserelated characteristics, sleep quality/duration, and the amount of physical activity on fatigue in adolescents with FMF. Methods. Seventy-one adolescents with FMF (13-18 years) were included. Children were examined regarding physical- and disease-related characteristics and completed patient-reported outcome measures (PROMs) regarding sleep quality/duration, physical activity levels, and fatigue. PedsQL-MFS was re-completed within the following 7-14 days. Results. PedsQL-MFS demonstrated excellent test-retest reliability (ICC in 95% CI: 0.877-0.958) and internal consistency (Cronbach`s α: 0.928). All items contributed to the total score (item-total correlation > 0.3). PedsQLMFS scores were significantly correlated to fatigue (r: -0.666, p < 0.001), physical activity (r: 0.373, p < 0.001), sleep quality (rs: 0.678, p < 0.001), and sleep duration (r: 0.473, p < 0.001). Being female, having attacks in the last six months, a sleep duration of less than seven hours, and engaging in less physical activity resulted in higher fatigue. Conclusions. PedsQL-MFS seems to be feasible for assessing fatigue in adolescents with FMF. Sex, recent attacks, sleep, and physical activity should be taken into consideration in the fatigue management of patients with FMF. https://turkjpediatr.org/article/view/70Fatiguechildfamilial Mediterranean feverphysical activitysleep
spellingShingle Devrim Can Saraç
Ece Pastutmaz
Sena Kongur
Cennet Hanım Karakurt
İdil Akar
İsrafil İnanç
Özge Altuğ Gücenmez
Belde Kasap Demir
Serkan Metin
Deniz Bayraktar
Assessing fatigue and related factors in adolescents with familial Mediterranean fever (FMF): psychometric properties of the PedsQL Multidimensional Fatigue Scale
The Turkish Journal of Pediatrics
Fatigue
child
familial Mediterranean fever
physical activity
sleep
title Assessing fatigue and related factors in adolescents with familial Mediterranean fever (FMF): psychometric properties of the PedsQL Multidimensional Fatigue Scale
title_full Assessing fatigue and related factors in adolescents with familial Mediterranean fever (FMF): psychometric properties of the PedsQL Multidimensional Fatigue Scale
title_fullStr Assessing fatigue and related factors in adolescents with familial Mediterranean fever (FMF): psychometric properties of the PedsQL Multidimensional Fatigue Scale
title_full_unstemmed Assessing fatigue and related factors in adolescents with familial Mediterranean fever (FMF): psychometric properties of the PedsQL Multidimensional Fatigue Scale
title_short Assessing fatigue and related factors in adolescents with familial Mediterranean fever (FMF): psychometric properties of the PedsQL Multidimensional Fatigue Scale
title_sort assessing fatigue and related factors in adolescents with familial mediterranean fever fmf psychometric properties of the pedsql multidimensional fatigue scale
topic Fatigue
child
familial Mediterranean fever
physical activity
sleep
url https://turkjpediatr.org/article/view/70
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