Comparing the immune response and protective effect of COVID-19 vaccine under different vaccination strategies

Although highly infectious respiratory viral infections spread rapidly, humans have evolved a precise and complex immune mechanism to deal with respiratory viruses, with strong intrinsic, highly adaptive and specific humoral and cellular immunity. At the same time, vaccination against Severe Acute R...

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Main Authors: Tianyi Zhao, Xiaoping Huang, Yuelong Shu
Format: Article
Language:English
Published: Taylor & Francis Group 2023-12-01
Series:Human Vaccines & Immunotherapeutics
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Online Access:https://www.tandfonline.com/doi/10.1080/21645515.2023.2273155
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author Tianyi Zhao
Xiaoping Huang
Yuelong Shu
author_facet Tianyi Zhao
Xiaoping Huang
Yuelong Shu
author_sort Tianyi Zhao
collection DOAJ
description Although highly infectious respiratory viral infections spread rapidly, humans have evolved a precise and complex immune mechanism to deal with respiratory viruses, with strong intrinsic, highly adaptive and specific humoral and cellular immunity. At the same time, vaccination against Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is one of the most cost-effective and efficient means of preventing morbidity, severe illness, and death from Coronavirus disease 2019 (COVID-19). As the global epidemic of COVID-19 continues to evolve and vaccines are being developed, it is important to conduct studies on immunization strategies to optimize vaccination strategies when appropriate. This review was conducted to investigate the relationship between the immune response and the protective effect of different vaccination scenarios (including booster, sequential and hybrid immunity), and to provide a basis for the optimization of vaccination strategies and the development of new vaccines in the future.
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publishDate 2023-12-01
publisher Taylor & Francis Group
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series Human Vaccines & Immunotherapeutics
spelling doaj-art-fef63076b7764f47b00a0ac9f1ef84b72025-08-20T02:03:27ZengTaylor & Francis GroupHuman Vaccines & Immunotherapeutics2164-55152164-554X2023-12-0119310.1080/21645515.2023.2273155Comparing the immune response and protective effect of COVID-19 vaccine under different vaccination strategiesTianyi Zhao0Xiaoping Huang1Yuelong Shu2School of Public Health (Shenzhen), Shenzhen Campus of Sun Yat-sen University, Shenzhen, ChinaSchool of Public Health (Shenzhen), Shenzhen Campus of Sun Yat-sen University, Shenzhen, ChinaSchool of Public Health (Shenzhen), Shenzhen Campus of Sun Yat-sen University, Shenzhen, ChinaAlthough highly infectious respiratory viral infections spread rapidly, humans have evolved a precise and complex immune mechanism to deal with respiratory viruses, with strong intrinsic, highly adaptive and specific humoral and cellular immunity. At the same time, vaccination against Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is one of the most cost-effective and efficient means of preventing morbidity, severe illness, and death from Coronavirus disease 2019 (COVID-19). As the global epidemic of COVID-19 continues to evolve and vaccines are being developed, it is important to conduct studies on immunization strategies to optimize vaccination strategies when appropriate. This review was conducted to investigate the relationship between the immune response and the protective effect of different vaccination scenarios (including booster, sequential and hybrid immunity), and to provide a basis for the optimization of vaccination strategies and the development of new vaccines in the future.https://www.tandfonline.com/doi/10.1080/21645515.2023.2273155COVID-19 vaccineimmunization strategiesimmune response
spellingShingle Tianyi Zhao
Xiaoping Huang
Yuelong Shu
Comparing the immune response and protective effect of COVID-19 vaccine under different vaccination strategies
Human Vaccines & Immunotherapeutics
COVID-19 vaccine
immunization strategies
immune response
title Comparing the immune response and protective effect of COVID-19 vaccine under different vaccination strategies
title_full Comparing the immune response and protective effect of COVID-19 vaccine under different vaccination strategies
title_fullStr Comparing the immune response and protective effect of COVID-19 vaccine under different vaccination strategies
title_full_unstemmed Comparing the immune response and protective effect of COVID-19 vaccine under different vaccination strategies
title_short Comparing the immune response and protective effect of COVID-19 vaccine under different vaccination strategies
title_sort comparing the immune response and protective effect of covid 19 vaccine under different vaccination strategies
topic COVID-19 vaccine
immunization strategies
immune response
url https://www.tandfonline.com/doi/10.1080/21645515.2023.2273155
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AT xiaopinghuang comparingtheimmuneresponseandprotectiveeffectofcovid19vaccineunderdifferentvaccinationstrategies
AT yuelongshu comparingtheimmuneresponseandprotectiveeffectofcovid19vaccineunderdifferentvaccinationstrategies