Immunal and biochemical indexes in early diagnostics of chronic brain ischemia
The paper presents results of clinical and laboratory investigation of 106 patients with chronic brain ischemia (CBI) I—II stages, included detection levels of circulating desquamated endothelial cells, endothelin-1, autoantibodies to encephalitogenic protein, neuron-specific enolase and protein S10...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Siberian State Medical University (Tomsk)
2011-04-01
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| Series: | Бюллетень сибирской медицины |
| Subjects: | |
| Online Access: | https://bulletin.ssmu.ru/jour/article/view/1377 |
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| author | Ye. V. Nechunaeva G. I. Shumakher Ye. N. Vorobiyova A. V. Timoshnikov M. A. Khoreva |
| author_facet | Ye. V. Nechunaeva G. I. Shumakher Ye. N. Vorobiyova A. V. Timoshnikov M. A. Khoreva |
| author_sort | Ye. V. Nechunaeva |
| collection | DOAJ |
| description | The paper presents results of clinical and laboratory investigation of 106 patients with chronic brain ischemia (CBI) I—II stages, included detection levels of circulating desquamated endothelial cells, endothelin-1, autoantibodies to encephalitogenic protein, neuron-specific enolase and protein S100. Reliable changes of immune status as well as signs of endothelium dysfunction progressed with stage of CBI. Direct correlation between intensity of endothelium dysfunction and activity of neurodegererative process in brain was revealed. |
| format | Article |
| id | doaj-art-feee795226ae44bbb75a6784c09a2bf7 |
| institution | Kabale University |
| issn | 1682-0363 1819-3684 |
| language | English |
| publishDate | 2011-04-01 |
| publisher | Siberian State Medical University (Tomsk) |
| record_format | Article |
| series | Бюллетень сибирской медицины |
| spelling | doaj-art-feee795226ae44bbb75a6784c09a2bf72025-08-20T03:38:08ZengSiberian State Medical University (Tomsk)Бюллетень сибирской медицины1682-03631819-36842011-04-0110214214610.20538/1682-0363-2011-2-142-146889Immunal and biochemical indexes in early diagnostics of chronic brain ischemiaYe. V. Nechunaeva0G. I. Shumakher1Ye. N. Vorobiyova2A. V. Timoshnikov3M. A. Khoreva4КГУЗ «Диагностический центр Алтайского края»Алтайский государственный медицинский университетАлтайский государственный медицинский университетАлтайский государственный медицинский университетАлтайский государственный медицинский университетThe paper presents results of clinical and laboratory investigation of 106 patients with chronic brain ischemia (CBI) I—II stages, included detection levels of circulating desquamated endothelial cells, endothelin-1, autoantibodies to encephalitogenic protein, neuron-specific enolase and protein S100. Reliable changes of immune status as well as signs of endothelium dysfunction progressed with stage of CBI. Direct correlation between intensity of endothelium dysfunction and activity of neurodegererative process in brain was revealed.https://bulletin.ssmu.ru/jour/article/view/1377chronic brain ischemianeurodegererative processcirculating desquamated endothelial cellsendothelin-1neurospecific proteins |
| spellingShingle | Ye. V. Nechunaeva G. I. Shumakher Ye. N. Vorobiyova A. V. Timoshnikov M. A. Khoreva Immunal and biochemical indexes in early diagnostics of chronic brain ischemia Бюллетень сибирской медицины chronic brain ischemia neurodegererative process circulating desquamated endothelial cells endothelin-1 neurospecific proteins |
| title | Immunal and biochemical indexes in early diagnostics of chronic brain ischemia |
| title_full | Immunal and biochemical indexes in early diagnostics of chronic brain ischemia |
| title_fullStr | Immunal and biochemical indexes in early diagnostics of chronic brain ischemia |
| title_full_unstemmed | Immunal and biochemical indexes in early diagnostics of chronic brain ischemia |
| title_short | Immunal and biochemical indexes in early diagnostics of chronic brain ischemia |
| title_sort | immunal and biochemical indexes in early diagnostics of chronic brain ischemia |
| topic | chronic brain ischemia neurodegererative process circulating desquamated endothelial cells endothelin-1 neurospecific proteins |
| url | https://bulletin.ssmu.ru/jour/article/view/1377 |
| work_keys_str_mv | AT yevnechunaeva immunalandbiochemicalindexesinearlydiagnosticsofchronicbrainischemia AT gishumakher immunalandbiochemicalindexesinearlydiagnosticsofchronicbrainischemia AT yenvorobiyova immunalandbiochemicalindexesinearlydiagnosticsofchronicbrainischemia AT avtimoshnikov immunalandbiochemicalindexesinearlydiagnosticsofchronicbrainischemia AT makhoreva immunalandbiochemicalindexesinearlydiagnosticsofchronicbrainischemia |