Structural mechanism of proton conduction in otopetrin proton channel
Abstract The otopetrin (OTOP) proteins were recently characterized as extracellular proton-activated proton channels. Several recent OTOP channel structures demonstrated that the channels form a dimer with each subunit adopting a double-barrel architecture. However, the structural mechanisms underly...
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| Main Authors: | Ninghai Gan, Weizhong Zeng, Yan Han, Qingfeng Chen, Youxing Jiang |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2024-08-01
|
| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-024-51803-x |
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